Table 1.
NGS test showed somatic mutation of tumor issue
| Gene | Variant | Exon | Transcript | Mutation abundance |
|---|---|---|---|---|
| STK11 | p.D176Y (c.526G>T) | Exon 4 | NM_000455.4 | 11.41% |
| TP53 | p.M246V (c.736A>G) | Exon 7 | NM_000546.5 | 8.81% |
| ATM | p.L2633Ffs*23 (c.7898dupT) | Exon 53 | NM_000051.3 | 9.23% |
| CDH9 | p.W453* (c.1358_1359delGGinsAA) | Exon 8 | NM_016279.3 | 7.05% |
| POLH | p.R167* (c.499C>T) | Exon 5 | NM_006502.2 | 0.61% |
| STAG2 | p.N236S (c.707A>G) | Exon 9 | NM_001042749.1 | 12.67% |
| NCOR1 | p.T1661I (c.4982C>T) | Exon 34 | NM_006311.3 | 9% |
| FAT2 | p.S1047L (c.3140C>T) | Exon 1 | NM_001447.2 | 8.09% |
| IL7R | p.S351F (c.1052C>T) | Exon 8 | NM_002185.3 | 5.19% |
| ASXL1 | p.L1408F (c.4224G>C) | Exon 13 | NM_015338.5 | 4.31% |
| CTNNB1 | p.S341R (c.1023C>G) | Exon 7 | NM_001904.3 | 4.19% |
| KMT2C | p.G315V (c.944G>T) | Exon 7 | NM_170606.2 | 1.08% |
*
The mutated codon cannot be translated into an amino acid.