Figure 6.
Effects of crowding on the Omicron variant. (A) Distribution of transfer efficiencies for wildtype (Wuhan-Hu-1) and Omicron variants in the absence of crowding. The vertical dashed line provides a reference for comparing the mean transfer efficiency. (B) Corresponding fraction bound and unbound based on titrations of (rU)40 in the absence of crowding and fit to eq S17. Errors are from multiple independent repeats of the same condition. (C) Distribution of transfer efficiencies for wildtype (Wuhan-Hu-1) and Omicron variants in the presence of crowding. The vertical dashed line provides a reference for comparing the mean transfer efficiency. (D) Corresponding fraction bound and unbound based on titrations of (rU)40 in the presence of 15% w/v PEG 600 and fit to eq S17. Errors are from multiple independent repeats of the same condition.