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. 2023 Jun 19;14(3):1504–1524. doi: 10.21037/jgo-23-301

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2023 Journal of Gastrointestinal Oncology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Subtype identification based on HRGs in PCA. (A) CDF curve and (B) delta area in TCGA cohort; (C) heatmap representing the consensus matrix; (D) KM curves showing OS of 3 subtypes; (E) pathways enriched in cluster 1 in comparison with cluster 2. HRGs, hypoxia-related genes; PCA, pancreatic cancer; CDF, cumulative distribution function; TCGA, The Cancer Genome Atlas; KM, Kaplan–Meier; OS, overall survival.