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. 2023 Jul 10;13(30):20495–20511. doi: 10.1039/d3ra02248j

Plasma strategies used for the generation of multifunctional surfaces.

Reference Methods Substrate Cell experiments Biocompatibility/bioactivity
96 Oxygen plasma Quartz Bone marrow stromal cells (BMSCs) MC3T3-E1 cells Cell density increased from 34 ± 1 cells per mm2 to 78 ± 3 cells per mm2, obvious graded distribution, oriented migration
99 Argon plasma Poly(lactic-co-glycolic acid) (PLGA) N/A Water contact angle dropped from 70° to 42°
100 Argon and argon–oxygen plasma Nanofibers Fibroblast cells Further increase in the number of fibroblast cells (145 ± 9)
101 CH4, C2F6, oxygen General-purpose polystyrene (GPPS) S. aureus, E. coli Antibacterial activity R = 4.1146, has antibacterial effect
102 Diethyl phosphite (DEP) Titanium (Ti) C. Albicans and S. aureus L929 fibroblast cells 72 h of antifungal assay, 13 cfu mL−1 of S. aureus and no live C. albicans was observed, increased cell viability of L929 fibroblast cells (93%)
105 Nitrogen ion (PIII) Silk films Bovine arterial endothelial cells (BAECs) Cell adhesion on PIII treated silk films was 2.5 s fold higher than on untreated silk films, PIII-treated silk supported significantly higher cell proliferation
106 C, nitrogen (PIII) Zirconia BMSCs The number of cells on zirconia disks was significantly increased, the number of cells attached on surface was highest among the four groups (P < 0.05), C and N2-PIII promoted cell proliferation activity
107 Nitrogen ion (PIII) Silk films Plasma proteins Recombinantly expressed domain V of the human the rate and the amount of basement membrane proteoglycan perlecan (rDV) binding were greater on PIII silk, rDV bioactivity was retained following covalent immobilization on silk, rDV-functionalized PIII silk inhibits thrombogenic activity in whole blood systems