Table 2.

Effects of exogenous chemicals on corticosterone (CORT) release rate and mass-corrected total bufadienolide quantity (mcTBQ) of toad tadpoles.

Response	Treatment length (days)	Contrast	Estimate	SE	df	t	P
CORT release rate	2	exoCORT—MTP	–1.312	0.044	261	–30.067	<0.001
	2	EtOH—exoCORT	1.546	0.044	261	35.423	<0.001
	2	EtOH—MTP	0.234	0.044	261	5.376	<0.001
	6	exoCORT—MTP	–1.215	0.044	262	–27.711	<0.001
	6	EtOH—exoCORT	1.453	0.045	263	32.653	<0.001
	6	EtOH—MTP	0.238	0.043	262	5.491	<0.001
mcTBQ	2	exoCORT–—MTP	–0.024	0.028	264	–0.855	0.590
	2	EtOH—exoCORT	0.038	0.027	264	1.401	0.487
	2	EtOH—MTP	0.014	0.026	264	0.518	0.605
	6	exoCORT—MTP	0.062	0.031	264	1.991	0.071
	6	EtOH—exoCORT	–0.097	0.034	264	–2.898	0.012
	6	EtOH—MTP	–0.035	0.030	264	–1.194	0.233

Estimates of linear contrasts are differences between the mean values of tadpoles exposed to the solvent control (EtOH), exogenous CORT (exoCORT), or metyrapone (MTP). P values were corrected using the FDR method for each dependent variable. Significant differences are highlighted in bold.