TABLE 2.

Multivariable analysis of risk factors for pN2-3 nodal disease

Variable	OR	95% CI	P value*
Age
≥ 65 years	Ref
< 65 years	2.38	1.32-4.49	0.005
LVI
Absent	Ref
Present	5.29	2.72-11.2	< 0.001
Multifocal/centric
No	Ref
Yes	3.08	1.79-5.32	< 0.001
Tumor size
< 5 mm	0.00	NA	> 0.9
5 mm-1 cm	0.69	0.19-1.95	0.5
1 cm-2 cm	Ref
> 2 cm	5.51	3.05-10.4	< 0.001

^*Bold indicates values of significance

CI confidence interval, LVI lymphovascular invasion