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. 2023 Jul 10;11:32. doi: 10.1186/s40560-023-00681-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Radar chart of methylprednisolone equivalent dose for patients with acute respiratory distress syndrome weighing 60 kg on the initial day. The radar chart on the right is an enlarged view of a portion from the chart on the left. The orange line represents the activity of glucocorticoids, and the blue line represents the activity of mineralocorticoids. The steroid dose on the initial day (loading and maintenance doses) was based on the following randomized controlled trials: hydrocortisone [14], methylprednisolone (Steinberg et al.) [19], methylprednisolone (Meduri et al.) [20], and dexamethasone [17]. The potency of glucocorticoids and mineralocorticoids is shown as a methylprednisolone equivalent dose (mg per 60 kg body weight)