Table 2. Clinical presentation, lesion localisation and characteristics of patients with claudication and critical limb threatening ischaemia.
|
All patients (n=402) |
Patients with claudication (n=135) | Patients with CLTI (n=267) | p-values | |
|---|---|---|---|---|
| Target lesions (n=558) n=181 in patients with claudication, n=377 in CLTI patients | Lesion localisation, length, and presence of occlusion | |||
| Iliac artery lesions | 22 (4%) | 11 (6%) | 11 (3%) | 0.99 |
| Common femoral artery lesions | 52 (9%) | 26 (14%) | 26 (7%) | 0.99 |
| Femoropopliteal artery lesions | 307 (55%) | 130 (72%) | 177 (47%) | 0.007 |
| Below-the-knee (BTK) artery lesions | 177 (32%) | 14 (8%) | 163 (43%) | <0.001 |
| Lesion length (cm) | 20.6±14.3 | 16.4±10.2 | 22.6±13.5 | <0.001 |
| Occlusion length (cm)* | 12.8±10.3 | 13.2±8.5 | 14.6±11.0 | 0.35 |
| Patients with de novo lesions | 387 (96%) | 127 (94%) | 260 (97%) | 0.10 |
| Patients with ISR lesions** | 31 (8%) | 17 (13%) | 14 (5%) | 0.01 |
| Patients with ISR class I lesions | 9 (2%) | 5 (4%) | 4 (1%) | 0.16 |
| Patients with ISR class II lesions | 3 (1%) | 1 (1%) | 2 (1%) | 0.99 |
| Patients with ISR class III lesions | 19 (5%) | 11 (8%) | 8 (3%) | 0.02 |
| Patients with at least 1 total occlusion*** | 234 (58%) | 75 (56%) | 159 (60%) | <0.001 |
| Number of CTO lesions per patient | 1.1±0.3 | 1.0±1.1 | 1.1±0.4 | 0.05 |
| Retrograde recanalisation necessary | 57 (14%) | 25 (19%) | 32 (12%) | 0.07 |
| Re-entry device necessary | 4 (1%) | 1 (1%) | 3 (1%) | 0.71 |
| All patients N=402 | Phoenix device sizes used | |||
| 1.5 mm tracking (4 Fr) | 7 (2%) | 0 (0%) | 7 (3%) |
chi²=69.0 p<0.001 |
| 1.8 mm tracking (5 Fr) | 99 (25%) | 3 (2%) | 96 (36%) | |
| 2.2 mm tracking (6 Fr) | 214 (53%) | 84 (62%) | 130 (49%) | |
| 2.2 mm deflecting (6 Fr) | 25 (6%) | 11 (8%) | 14 (5%) | |
| 2.4 mm deflecting (7 Fr) | 57 (14%) | 35 (26%) | 22 (8%) | |
| All patients N=402 | Lesion complexity by the TASC classification | |||
| TASC B | 71 (18%) | 23 (17%) | 48 (18%) |
chi²=0.8 p=0.66 |
| TASC C | 223 (55%) | 79 (59%) | 144 (54%) | |
| TASC D | 108 (27%) | 33 (24%) | 75 (28%) | |
| All patients N=402 | PACSS score of the target lesions (0-4) | |||
| PACSS score 0/1 | 18 (4%) | 7 (%5) | 11 (4%) |
chi²=5.3 p=0.25 |
| PACSS score 2 | 61 (15%) | 22 (16%) | 39 (15%) | |
| PACSS score 3 | 134 (33%) | 36 (27%) | 98 (37%) | |
| PACSS score 4 | 189 (47%) | 70 (52%) | 119 (45%) | |
| *Considering only CTO lesions. **Additional de novo lesions may also be present. ***Including de novo lesions and ISR class III. CLTI: critical limb threatening ischaemia; CTO: chronic total occlusion; Fr: French; ISR: in-stent restenosis; NA: not applicable; PACSS: peripheral arterial calcium scoring system; TASC: Transatlantic Inter-Society Consensus | ||||