Table 3.
Changes in inflammatory factors after initiation of roxadustat
| Time | IL-1 (ng/L) | IL-6 (ng/L) | TNF-α (ng/L) | IFN-γ (ng/L) | ET (ng/L) |
|---|---|---|---|---|---|
| Baseline (M0) | 107.72 ± 17.54 | 36.54 ± 5.84 | 55.13 ± 10.58 | 52.28 ± 8.94 | 7.82 ± 1.94 |
| M1 | 85.13 ± 15.97 | 30.05 ± 5.41 | 44.14 ± 10.02 | 37.15 ± 9.11 | 6.11 ± 1.72 |
| M3 | 73.75 ± 16.26 | 28.84 ± 5.68 | 42.97 ± 9.93 | 35.42 ± 8.70 | 5.54 ± 1.55 |
| F value | 603.626 | 271.113 | 321.807 | 906.224 | 493.483 |
| P value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
M0: before roxadustat; M1: 1 month after initiation of roxadustat; M3: 3 months after initiation of roxadustat (end of study)