Table 1.
Baseline characteristics
| Characteristics | Non-general anesthesia (N = 429) | General anesthesia (N = 207) |
P Value |
|---|---|---|---|
| Median age- yr | 69.00 | 71.00 | 0.21 |
| Male sex- no. (%) | 241(56.18) | 118(57.00) | 0.84 |
| Medical history- no. (%) | |||
| Hypertension | 250(58.28) | 130(62.80) | 0.28 |
| Atrial fibrillation | 196(45.69) | 98(47.34) | 0.70 |
| Diabetes mellitus | 77(17.95) | 43(20.77) | 0.39 |
| Clinical status | |||
| NIHSS score, Median | 17.00 | 17.00 | 0.47 |
| Baseline SBP, Median | 144.00 | 148.00 | 0.06 |
| Pre-stroke mRS- no. (%) | 0.45 | ||
| 0 | 392(91.38) | 195(94.20) | |
| 1 | 29(6.76) | 7(3.38) | |
| 2 | 8(1.86) | 5(2.42) | |
| ASPECTS | 9.00 | 8.00 | 0.009 |
| Bridging therapy- no. (%) | |||
| EVT | 210(48.95) | 105(50.72) | 0.68 |
| EVT + IVT | 219(51.05) | 102(49.28) | |
| Etiology- no. (%) | 0.66 | ||
| Cardioembolic | 189(44.06) | 94(45.41) | |
| Intracranial atherosclerosis | 27(6.29) | 18(8.70) | |
| Undetermined | 170(39.63) | 76(36.71) | |
| Occlusion site- no. (%) | 0.38 | ||
| ICA | 157(37.12) | 66(32.04) | |
| M1 | 215(50.83) | 119(57.77) | |
| M2 | 50(11.82) | 21(10.19) | |
| Workflow intervals- median, min | |||
| Onset to triage | 108.00 | 126.00 | 0.08 |
| To intravenous alteplase | 180.00 | 190.00 | 0.10 |
| To randomization | 169.00 | 177.00 | 0.08 |
| To reperfusion | 238.00 | 262.00 | 0.0002 |
| Triage to randomization | 49.00 | 49.00 | 0.695 |
| To intravenous alteplase | 60.00 | 58.00 | 0.54 |
| To groin puncture | 84.00 | 85.00 | 0.30 |
| To reperfusion | 148.50 | 169.00 | 0.0003 |
| Randomization to groin puncture | 32.00 | 36.00 | 0.09 |
| To reperfusion | 93.00 | 116.00 | < 0.0001 |
| Groin puncture to reperfusion | 59.00 | 72.00 | 0.002 |
ASPECTS Alberta Stroke Program Early CT score; SBP systolic blood pressure; ICA internal carotid artery; M middle cerebral artery; NIHSS National Institutes of Health Stroke Scale; EVT endovascular treatment; IVT intravenous treatment