Fig. 1.

Circulating redox and inflammatory markers measured at baseline, end of surgery and day-1 after major surgery. Perioperative changes in A TFT adjusted to protein (n = 48), B FRAP (n = 47), C TBARS concentration (n =4 9), D HNE adjusted to protein (n = 44), E 8-isoprotanes (n = 48), F cGMP (n = 43), G nitrite (n = 46), H nitrate (n = 47), I RxNO (n = 49), J IL-6 (n = 51), K TNF-α (n = 51). All panels are presented as median and IQR, except A, B and E are presented as mean and SD, and y-axis for J is logarithmic