Table 1.
Demographic characteristics and laboratory data of the study population.
| Clinical characteristics | All patients (n = 369) | Survivors (n = 304) | Non-survivors (n = 65) | p Value |
|---|---|---|---|---|
| Male (n, %) | 214 (58.0%) | 179 (58.9%) | 35 (53.4%) | .455 |
| Age (years) | 47 (37, 59) | 45 (35, 56) | 63 (52, 71) | <.001 |
| BMI (kg/m2) | 22.50 ± 2.99 | 22.43 ± 3.00 | 22.82 ± 2.95 | .348 |
| MAP (mmHg) | 111 (102, 120) | 110 (102, 120) | 108 (100, 120) | .325 |
| Diabetes mellitus (n, %) | 61 (16.5%) | 41 (13.5%) | 20 (30.8%) | .001 |
| Current smoking (n, %) | 56 (15.2%) | 41 (13.5%) | 15 (23.1%) | .050 |
| CVD history (n, %) | 41 (11.1%) | 24 (7.9%) | 17 (26.2%) | <.001 |
| KF causes | .001 | |||
| Glomerulonephritis (n, %) | 205 (55.6%) | 182 (59.9%) | 23 (35.4%) | |
| Diabetic nephropathy (n, %) | 34 (9.2%) | 22 (7.2%) | 12 (18.5%) | |
| Hypertension nephropathy (n, %) | 36 (9.8%) | 26 (8.6%) | 10 (15.4%) | |
| Other/unknown (n, %) | 94 (25.5%) | 74 (24.3%) | 20 (30.8%) | |
| White blood count (×109/L) | 6.07 (4.94, 7.65) | 6.06 (4.93, 7.53) | 6.27 (4.96, 8.22) | .293 |
| Hemoglobin (g/dL) | 8.19 (6.90, 9.30) | 8.20 (6.97, 9.30) | 8.03 (6.75, 9.19) | .367 |
| Platelet count (×109/L) | 161 (125, 208) | 159 (124, 207) | 170 (137, 221) | .098 |
| Neutrophil count (×109/L) | 4.23 (3.28, 5.52) | 4.16 (3.25, 5.47) | 4.66 (3.46, 6.63) | .061 |
| Lymphocyte count (×109/L) | 1.13 (0.83, 1.53) | 1.18 (0.85, 1.58) | 1.02 (0.73, 1.27) | .014 |
| Monocyte count (×109/L) | 0.35 (0.25, 0.48) | 0.35 (0.25, 0.46) | 0.40 (0.25, 0.55) | .138 |
| AISI | 205.20 (116.71, 369.63) | 193.91 (106.55, 342.85) | 263.19 (145.52, 626.60) | .003 |
| SII | 568.45 (371.07, 979.65) | 540.84 (355.67, 874.13) | 772.91 (483.89, 1300.39) | <.001 |
| SIRI | 1.2987 (0.8216, 2.0279) | 1.2769 (0.7928, 1.8302) | 1.6469 (1.0335, 2.9323) | .005 |
| Albumin (g/L) | 33.4 (29.8, 36.5) | 33.9 (29.8, 36.5) | 32.4 (28.9, 35.8) | .128 |
| Globulin (g/L) | 25.8 (22.8, 29.0) | 25.6 (22.5, 28.7) | 27.5 (23.8, 30.4) | .005 |
| BUN (mmol/L) | 30.50 ± 10.45 | 30.74 ± 10.62 | 29.38 ± 9.65 | .343 |
| Serum creatinine (μmol/L) | 800.7 (657.1, 975.0) | 811.0 (673.3, 990.6) | 725.0 (625.2, 873.0) | .023 |
| Uric acid (μmol/L) | 496.02 ± 134.80 | 497.77 ± 138.87 | 487.80 ± 114.45 | .589 |
| RKF (ml/min/1.73m2) | 5.47 (4.30, 6.97) | 5.44 (4.31, 6.96) | 5.52 (4.10, 7.11) | .856 |
| Corrected calcium (mmol/L) | 2.02 (1.79, 2.18) | 2.02 (1.80, 2.17) | 2.01 (1.72, 2.20) | .583 |
| Phosphate (mmol/L) | 1.89 (1.56, 2.34) | 1.89 (1.56, 2.35) | 1.89 (1.52, 2.16) | .719 |
| iPTH (Pg/mL) | 236.6 (110.3, 418.0) | 239.8 (110.7, 432.8) | 230.3 (98.5, 343.1) | .468 |
| Prealbumin (mg/L) | 269 (222, 304) | 273 (232, 308) | 232 (191, 283) | <.001 |
| CRP (mg/L) | 4.9 (3.6, 8.4) | 4.6 (3.6, 7.6) | 6.4 (3.7, 15.0) | .012 |
| Cholesterol (mmol/L) | 4.13 (3.49, 4.85) | 4.11 (3.46, 4.81) | 4.25 (3.57, 5.15) | .162 |
| Triglyceride (mmol/L) | 1.69 (1.18, 2.30) | 1.70 (1.19, 2.32) | 1.67 (1.12, 2.23) | .772 |
| HDL-C (mmol/L) | 0.92 (0.76, 1.12) | 0.92 (0.76, 1.12) | 0.95 (0.77, 1.14) | .517 |
| LDL-C (mmol/L) | 2.07 (1.65, 2.49) | 2.05 (1.62, 2.48) | 2.10 (1.78, 2.64) | .284 |
| apo-A1 (g/L) | 1.13 ± 0.20 | 1.13 ± 0.20 | 1.17 ± 0.20 | .112 |
| apo-B (g/L) | 0.86 (0.70, 1.01) | 0.85 (0.70, 1.00) | 0.89 (0.75, 1.08) | .201 |
| EF (%) | 62 (59, 64) | 62 (59, 64) | 61 (57, 63) | .071 |
| Follow-up time (months) | 32.83 (19.63, 54.23) | 32.73 (20.47, 53.93) | 34.30 (17.45, 54.80) | .993 |
Notes: Continuous variables are presented as mean ± standard deviation for normal distribution data or median (interquartile range) for non-normal distribution data. BMI: body mass index; MAP: mean arterial pressure; CVD: cardiovascular disease; BUN: blood urea nitrogen; RKF: residual kidney function; iPTH: intact parathyroid hormone; CRP: C-reactive protein; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; apo-A1: apolipoprotein A1; apo-B: apolipoprotein B; EF: ejection fraction; AISI: aggregate index of systemic inflammation; SII: systemic immune-inflammation index; SIRI: systemic inflammation response index.