Table 3.
Univariate Cox analysis of all-cause mortality in peritoneal dialysis patients.
| Variables | Univariate analysis |
|
|---|---|---|
| HR (95% CI) | p Value | |
| Gender (female vs. male) | 0.773 (0.471, 1.268) | .308 |
| Age (≥60 years old) | 4.487 (2.728, 7.379) | <.001 |
| BMI (kg/m2) | 1.078 (0.995, 1.167) | .065 |
| MAP (mmHg) | 0.997 (0.982, 1.013) | .735 |
| Hypertension | 3.971 (0.546, 28.881) | .173 |
| Diabetes mellitus | 3.687 (2.146, 6.335) | <.001 |
| Current smoking | 2.132 (1.195, 3.804) | .010 |
| CVD history | 3.033 (1.738, 5.292) | <.001 |
| White blood count (×109/L) | 1.064 (0.961, 1.178) | .230 |
| Hemoglobin (g/dL) | 1.040 (1.007, 1.075) | .018 |
| Platelet (×109/L) | 1.006 (1.003, 1.010) | .001 |
| Neutrophil (×109/L) | 1.081 (0.975, 1.198) | .138 |
| Lymphocytes (×109/L) | 0.736 (0.435, 1.245) | .253 |
| Monocyte (×109/L) | 2.095 (0.623, 7.047) | .232 |
| Albumin (g/L) | 0.976 (0.929, 1.026) | .338 |
| Globulin (g/L) | 1.056 (1.007, 1.106) | .024 |
| BUN (mmol/L) | 0.978 (0.953, 1.004) | .101 |
| Serum creatinine (μmol/L) | 0.999 (0.998, 1.000) | .035 |
| Uric acid (μmol/L) | 0.999 (0.997, 1.001) | .161 |
| RKF (ml/min/1.73m2) | 1.051 (0.933, 1.183) | .413 |
| Corrected calcium (mmol/L) | 1.047 (0.507, 2.161) | .902 |
| Phosphate (mmol/L) | 0.892 (0.597, 1.333) | .577 |
| iPTH (Pg/mL) | 1.000 (0.999, 1.001) | .537 |
| Prealbumin (mg/L) | 0.992 (0.988, 0.996) | <.001 |
| CRP (mg/L) | 1.021 (1.008, 1.034) | .002 |
| Cholesterol (mmol/L) | 1.274 (1.035, 1.567) | .022 |
| Triglyceride (mmol/L) | 1.009 (0.806, 1.263) | .939 |
| HDL-C (mmol/L) | 1.439 (0.659, 3.144) | .362 |
| LDL-C (mmol/L) | 1.555 (1.156, 2.092) | .004 |
| apo-A1 (g/L) | 1.219 (0.309, 4.804) | .777 |
| apo-B (g/L) | 3.840 (1.546, 9.541) | .004 |
| EF (%) | 0.972 (0.936, 1.010) | .149 |
| AISI > 378.59 | 2.226 (1.358, 3.649) | .002 |
| SII > 463.77 | 2.794 (1.490, 5.238) | .001 |
| SIRI > 2.0903 | 2.070 (1.264, 3.389) | .004 |
Note: BMI: body mass index; MAP: mean arterial pressure; CVD: cardiovascular disease; BUN: blood urea nitrogen; RKF: residual kidney function; iPTH: intact parathyroid hormone; CRP: C-reactive protein; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; apo-A1: apolipoprotein A1; apo-B: apolipoprotein B; EF: ejection fraction; AISI: aggregate index of systemic inflammation; SII: systemic immune-inflammation index; SIRI: systemic inflammation response index.