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. 2023 Jul 7;45(1):2160348. doi: 10.1080/0886022X.2022.2160348

Table 4.

Hazard ratios of blood cell count-derived inflammation indexes by multivariate Cox analysis of inflammation indexes.

  Model 1
Model 2
Model 3
HR (95% CI) p Value HR (95% CI) p Value HR (95% CI) p Value
AISI > 378.59 2.330 (1.404, 3.866) .001 2.494 (1.490, 4.175) .001 2.508 (1.505, 4.179) <.001
SII > 463.77 3.320 (1.691, 6.519) <.001 2.749 (1.448, 5.221) .002 3.477 (1.785, 6.775) <.001
SIRI > 2.0903 1.951 (1.184, 3.215) .009 1.852 (1.100, 3.118) .020 1.711 (1.012, 2.895) .045

Notes: Model 1: adjusted for age, diabetes mellitus, CVD history, current smoking; Model 2: adjusted for model 1 + hemoglobin, globulin, creatinine, prealbumin, CRP; Model 3: adjusted for model 2 + cholesterol, LDL-C, apo-B. AISI: aggregate index of systemic inflammation; SII: systemic immune-inflammation index; SIRI: systemic inflammation response index; CRP: C-reactive protein; CVD: cardiovascular disease; LDL-C: low-density lipoprotein cholesterol; apo-B: apolipoprotein B.