Fig. 4. (A) Sectioned MTS showing hypoxic staining using pimonidazole, where the presence of the brown colour indicates hypoxia. (B) Schematic correlating hypoxia and NP uptake within the MTS based on (A). The outer, actively proliferating layer of cells of the MTS are coloured light orange, the quiescent and hypoxic cells are dark orange. The gold spheres illustrate the nanotags. Scale bar is 200 μm.
