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. 2023 Jun 26;14:1196892. doi: 10.3389/fimmu.2023.1196892

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Copyright © 2023 Zhao, Ding, Tran, Chai and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CytoTrace and inferred copy number variation (CNV) analysis of melanoma cell subtypes. (A) Differentiation of melanoma cell subtypes. (B) The lowest differentiation of C5 Melanoma MAGEA4 and the highest differentiation of C4 Melanoma CORO1A can be observed from the graph. (C, D) Differences in cell stemness scored per cell by AUCell among melanoma cell subtypes, C4 Melanoma CORO1A has the lowest cell stemness. (E) The heatmap displayed large-scale CNVs of melanoma cells. The red color represents a high CNV level, and the blue represents a low CNV level. ****P < 0.0001.