Table 1.
Baseline characteristics of the whole cohort.
| Baseline characteristics | Total patients (n=1535) | Cohorts before PSM | Cohort of PS0 after PSM $ (n=342) | |
|---|---|---|---|---|
| PS 0 (n=1193) | PS 1 (n=342) | |||
| Age, <70/≥70, n (%) | 1416 (92.2)/119 (7.8) | 1102 (92.4)/91 (7.6) | 314 (91.8)/28 (8.2) | 310 (90.6)/32 (9.4) |
| Gender, male/female, n (%) | 1283 (83.6)/252 (16.4) | 995 (83.4)/198 (16.6) | 288 (84.2)/54 (15.8) | 295 (86.3)/47 (13.7) |
| Etiology, HBV (+)/HBV (-), n (%) | 1426 (92.9)/109 (7.1) | 1110 (93.0)/83 (7.0) | 316 (92.4)/26 (7.6) | 314 (91.8)/28 (8.2) |
| Child-pugh score, 5/6, n (%) * | 1392 (90.7)/143 (9.3) | 1097 (92.0)/96 (7.9) | 295 (86.3)/47 (13.7) | 311 (90.9)/31 (9.1) |
| AFP, <400/≥400 ng/ml, n (%) * | 1089 (70.9)/446 (29.1) | 858 (71.9)/335 (28.1) | 231 (67.5)/111 (32.5) | 231 (67.5)/111 (32.5) |
| Tumor number, 1/>1, n (%) | 1491 (97.1)/44 (2.9) | 1156 (96.9)/37 (3.10) | 335 (98.0)/7 (2.0) | 336 (98.2)/6 (1.8) |
| Tumor size, ≤5/>5 cm, n (%) * | 951 (62.0)/584 (38.0) | 794 (66.5)/399 (33.5) | 157 (45.9)/185 (54.1) | 157 (45.9)/185 (54.1) |
| Albumin, >35/≤35 g/L, n (%) | 1426 (92.9)/109 (7.1) | 1106 (92.7)/87 (7.3) | 320 (93.6)/22 (6.4) | 320 (93.6)/22 (6.4) |
| TBIL, ≤17.1/>17.1 μmol/L, n (%) | 974 (63.5)/561 (36.5) | 749 (62.8)/444 (37.2) | 225 (65.8)/117 (34.2) | 214 (62.6)/128 (37.4) |
| AST, U/L, median (IQR) * | 35.0 (26.0-49.2) | 34.0 (26.0-48.0) | 37.0 (27.0-57.0) | 34.0 (27.0-49.0) |
| ALT, U/L, median (IQR) | 33.0 (23.0-51.0) | 33.0 (23.0-51.0) | 34.0 (24.0-54.0) | 34.0 (24.0-52.0) |
| WBC, ×109/L, median (IQR) * | 5.3 (4.2-6.6) | 5.2 (4.1-6.4) | 5.5 (4.4-7.0) | 5.6 (4.6-6.8) |
| BUN, mmol/L, median (IQR) | 5.4 (4.4-6.4) | 5.3 (4.5-6.4) | 5.3 (4.4-6.4) | 5.4 (4.5-6.4) |
| PLT, ×109/L, median (IQR)* | 146.0 (107.0-188.0) | 142.0 (104.0-183.0) | 158.0 (114.7-207.8) | 154.0 (118.0-194.0) |
| INR, median (IQR) | 1.02 (0.97-1.07) | 1.02 (0.97-1.07) | 1.02 (0.95-1.07) | 1.00 (0.97-1.02) |
* Variables with significant difference between PS 0 and PS 1 cohorts (P<0.05).
$ Variables with significant difference between PS 0 and PS 1 cohorts (P<0.05) after a 1:1 propensity score matching (PSM; caliper value of 0.2).
HCC, hepatocellular carcinoma; PS, performance status; HBV, hepatitis B virus; AFP, alpha fetoprotein; TBIL, total bilirubin; AST, aspartate aminotransferase; ALT, alamine aminotransferase; WBC, white blood cell; BUN, blood urea nitrogen; PLT, platelet count; INR, international normalized ratio.