Table 4.
Risk stratification | Univariate analysis | Multivariate analysis | Variables included in multivariate analysis* | ||
---|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | ||
Low-risk stratification | |||||
Model 1 | 0.74 (0.44-1.22) | 0.235 | 0.73 (0.44-1.22) | 0.242 | Age, Tumor number |
Model 2 | 0.80 (0.41-1.56) | 0.515 | 0.78 (0.39-1.53) | 0.473 | AST, ALT |
Model 3 | 0.80 (0.41-1.56) | 0.515 | 0.79 (0.40-1.55) | 0.409 | AST, ALT |
Medium-risk stratification | |||||
Model 1 | 0.48 (0.34-0.67) | <0.001 | 0.49 (0.35-0.68) | <0.001 | AFP |
Model 2 | 0.44 (0.28-0.70) | <0.001 | 0.46 (0.29-0.72) | 0.001 | AFP |
Model 3 | 0.44 (0.28-0.70) | <0.001 | 0.45 (0.29-0.71) | 0.001 | AFP |
High-risk stratification | |||||
Model 1 | 0.72 (0.49-1.07) | 0.102 | 0.71 (0.81-1.06) | 0.096 | PLT |
Model 2 | 0.62 (0.39-1.01) | 0.056 | 0.63 (0.39-1.03) | 0.066 | BUN, PLT |
Model 3 | 0.62 (0.39-1.01) | 0.056 | 0.63 (0.38-1.02) | 0.062 | BUN, PLT |
* Variables with statistically significant differences in univariate analysis and included in multivariate analysis for adjustment.
Model 1: multivariate analysis with baseline characteristics for original patients.
Model 2: multivariate analysis with baseline characteristics for patients after PSM.
Model 3: multivariate analysis with propensity score for patients after PSM.
HR, hazard ratio; CI, confidence interval; AST, aspartate aminotransferase; ALT, alamine aminotransferase; PLT, platelet count; BUN, blood urea nitrogen; AFP, alpha-fetoprotein.