Table 3.
Effect of the extract on the hematological parameters in the suppressive test.
| Red blood cells | White blood cells | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | Dosage | RBC | Hb | HCT (%) | MCV(fl) | MCH | MCCH | WBC | NEU | EOS | BASO | LYM | MON |
| Negative control | 1% DMSO | 2.6 ± 0.92b | 7.3 ± 4.44 | 15.6 ± 9.924 | 47.1 ± 4.69 | 21.9 ± 1.7 | 47.1 ± 2.5 | 4.3 ± 0.78 | 3.6 ± 5.04 | 0.4 ± 0.38 | 0.44 ± 0.77 | 65.61 ± 6.59 | 29.94 ± 12.77 |
| Chloroquine | 5 mg/kg | 6.3 ± 0.47a | 13.5 ± 1.25 | 29.7 ± 2.3 | 47.2 ± 0.2 | 21.3 ± 0.4 | 45.3 ± 0.8 | 20.3 ± 12.9 | 18 ± 6.5 | 1.38 ± 1.21 | 1.21 ± 0.24 | 44.57 ± 4.258 | 34.7 ± 9.57 |
| Ethanolic extract | 125 mg/kg | 4.1 ± 1.2a | 11.5 ± 1.75 | 23.9 ± 4.86 | 48.3 ± 2.55 | 23.4 ± 2.0 | 48.5 ± 2.9 | 9.9 ± 1.26 | 57.3 ± 33.8 | 0.9 ± 0.73 | 0.31 ± 0.42 | 38 ± 26.71 | 20.8 ± 19.48 |
| 250 mg/kg | 5.19 ± 0.76a | 10.3 ± 1.99 | 23.9 ± 4.82 | 45.8 ± 3.05 | 19.8 ± 1.6 | 43.6 ± 5.6 | 20.08 ± 6 | 8.7 ± 9.16 | 0.7 ± 0.41 | 0.7 ± 0.69 | 35.7 ± 21.02 | 54.7 ± 24.5 | |
| 500 mg/kg | 5.8 ± 2.27a | 11.8 ± 3.89 | 25.83 ± 9.5 | 44.9 ± 2.81 | 20.7 ± 2.1 | 46.17 ± 1.9 | 19.09 ± 6.5 | 5.54 ± 5.6 | 0.72 ± 0.76 | 0.47 ± 0.61 | 45.95 ± 1.104 | 47.32 ± 6.2 | |
| Neutral | Water | 6.76 ± 0.54a | 14.5 ± 0.35 | 31.70 ± 1.83 | 47.1 ± 3.5 | 21.5 ± 1.4 | 45.7 ± 1.65 | 11.38 ± 3.3 | 51.44 ± 39.9 | 3.6 ± 2.25 | 0.61 ± 0.49 | 25.71 ± 21.66 | 18.64 ± 21.64 |
Values are given as mean ± SD (n = 3). a,bValues carrying the same superscript letter are not significantly different at p < 0.05.
RBC: red blood cells; MCV: mean corpuscular volume; HBG: haemoglobin, WBC: white blood cells; HCT: hematocrit; MCH: mean corpuscular content in haemoglobin; MCCH: mean corpuscular concentration in haemoglobin; MO: monocytes; NEU: neutrophils; EOS: eosinophils; BASO: basophils; LY: Lymphocytes; Hb: Haemoglobin.