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. 2023 Jun 28;15(12):5279–5289. doi: 10.18632/aging.204844

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Copyright: © 2023 Rocha et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Effect of UV-light on levels of T14 in skin. (A) Immunohistochemistry of AChE T14 peptide expression is higher in aged photo-protected (50 to 70 years old) skin compared to photo-aged skin (50 to 70 years old. N=10 in each group. (B) Average number of epidermal cells with a positive AChE T14 peptide antibody stain. Aged (photo-protected) skin samples have a significantly higher expression (p value of 0.00265) of T14 positive cells compared to its expression in age matched, photo-aged skin samples. (C) Average number of epidermal cells with a positive AChE T14 peptide antibody stain normalized by epidermal area. Aged (photo-protected) skin samples have a significantly higher expression (p value of 0.00176) of T14 positive cells per epidermal area compared to its expression in age-matched photo-exposed skin. (D) Immunohistochemistry of AChE T14 peptide expression is higher in 1 outlier of the aged group.