Observed cases. Full analysis set. Data from rescued patients were censored after rescue. Patients who did not have available BCVA at week 52 were excluded. BCVA best-corrected visual acuity, CST central subfield thickness, DRSS Diabetic Retinopathy Severity Scale, IAI intravitreal aflibercept injection, ETDRS Early Treatment Diabetic Retinopathy Study, Δ difference.