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. 2022 Nov 12;37(10):2101–2108. doi: 10.1038/s41433-022-02297-8

Table 4.

Summary of descriptive characteristics by prognosis, stratified into good and poor outcome, and their association with final visual acuity of NLP and development of phthisis bulbi.

Overall N (%) Good outcomea N (%) Poor outcomea N (%) P value Final BCVA NPL N (%) P value Phthisis Bulbi N (%) P value
Sex, N = 198 0.008
  Female 48 (24.2) 8 (16.6) 40 (83.3)
  Male 150 (75.8) 58 (38.6) 92 (61.3)
Laterality, N = 198 0.388
  Right eye 85 (42.9) 25 (29.4) 60 (70.6)
  Left eye 113 (57.1) 41 (36.3) 72 (63.7)
Age (years), N = 198 <0.001
  Median [25th; 75th] 54.0 [33.0;77.0] 37.0 [16.5;54.2] 69.0 [46.0;82.2]
  0–30 43 (21.7) 23 (53.5) 20 (46.5)
  31–60 71 (35.9) 32 (45.1) 39 (54.9)
  61–100 84 (42.4) 11 (13.1) 73 (86.9)
History of eye surgery, N = 198
  Cataract extraction 57 (28.8) 9 (15.8) 48 (84.2) 0.002
  Corneal transplant 24 (12.1) 5 (20.8) 19 (79.2) 0.248
Type of injury, N = 198 <0.001 <0.001 <0,001
  Rupture 118 (59.6) 19 (16.1) 99 (83.9) 76 (64.4) 69 (58.5)
  Penetration 56 (28.3) 34 (60.7) 22 (39.3) 15 (26.8) 13 (23.2)
  IOFB 24 (12.1) 13 (54.2) 11 (45.8) 6 (25.0) 6 (25.0)
Mechanism, N = 198 <0.001 <0.001 0.007
  Others 70 (35.4) 37 (52.9) 33 (47.1) 21 (30.0) 21 (30.0)
  Fall 66 (33.3) 6 (9.09) 60 (90.9) 47 (71.2) 39 (59.1)
  Work tool/machinery 36 (18.2) 14 (38.9) 22 (61.1) 15 (41.7) 15 (41.7)
  Assaults/fights 26 (13.1) 9 (34.6) 17 (65.4) 14 (53.8) 13 (50.0)
Zone, N = 198 <0.001 <0.001 <0.001
  I 74 (37.4) 39 (52.7) 35 (47.3) 16 (21.6) 13 (17.6)
  II 65 (32.8) 22 (33.8) 43 (66.2) 34 (52.3) 31 (47.7)
  III 59 (29.8) 5 (8.5) 54 (91.5) 47 (79.6) 44 (74.6)
Initial BCVA, N = 180 <0.001 <0.001 <0.001
  ≥ LP 101 (56.1) 52 (51.5) 49 (48.5) 24 (23.8) 21 (20.8)
  NLP 79 (43.9) 2 (2.53) 77 (97.5) 70 (88.6) 63 (79.7)
OTS score, N = 179
 Median [25th; 75th] 37.0 [16.0;60.0] 70.0 [59.0;90.0] 27.0 [16.0;39.0]
  0–44 103 (57.5) 2 (1.9) 101 (98.1)
  45–65 33 (18.4) 14 (42.4) 19 (57.6)
  66–80 21 (11.7) 17 (80.9) 4 (19.1)
  81–91 13 (7.26) 11 (84.6) 2 (15.4)
  92–100 9 (5.03) 9 (100.0) 0 (0.00)
OTS category, N = 179 <0.001
  > 2 43 (24.0) 37 (86.0) 6 (14.0)
  ≤ 2 136 (76.0) 16 (11.7) 120 (88.3)
Delay to surgery (hours) N = 196 0.880
  ≤ 6 102 (52.0) 36 (60.0) 66 (30.0)
  7–12 60 (30.6) 19 (26.0) 41 (74.0)
  >12 34 (17.4) 11 (16.9) 23 (83.1)
Length of stay (days), N = 198 0.628
  1 60 (30.3) 20 (33.3) 40 (66.6)
  2–4 73 (36.9) 27 (37.0) 46 (63.0)
  >4 65 (32.8) 19 (29.2) 46 (70.8)
Complications
  Lens damage 158 (79.8) 30 (19.0) 128 (81.0) <0.001
  Choroidal/retinal detachment 138 (69.7) 19 (13.7) 119 (86.3) <0.001
  Graft failure 15 (7.58) 2 (13.3) 13 (86.6) 0.154
  Infection 11 (5.56) 0 (0.00) 11 (100.0) 0.019
  Ocular hypertension 28 (14.1) 10 (35.7) 18 (64.3) 0.943
Further surgery, N = 198 0.880 0.305 0.473
  Yes 90 (45.5) 29 (32.2) 61 (67.8) 57 (52.8) 51 (47.2)
  No 108 (54.5) 37 (34.3) 71 (65.7) 40 (44.4) 37 (41.1)

BCVA best corrected visual acuity, NLP no light perception, LP light perception, OTS Ocular Trauma Score, IOFB intraocular foreign body.

aFinal BCVA > 0.1 (decimal visual acuity) was considered a “good outcome”, and final BCVA ≤ 0.1 a “poor outcome”. In cases of visual acuity < 0.3 prior to the trauma, individuals with a final BCVA less than or equal to a third of their original BCVA were considered to have a “poor outcome”.