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. 2023 Jul 10;13:11181. doi: 10.1038/s41598-023-38379-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of B. coagulans MZY531 on ZO-1 intestinal barrier pathway in ileum of immunosuppressed mice. The protein expression of Claudin-1, Occludin and ZO-1 in the ileal were detected by western blot (A). The ratios of ZO-1/β-actin (B), Occludin/β-actin (C) and Claudin-1/β-actin (D) protein bands for each region were quantified using densitometry and presented in the graph. All data were statistically analyzed using a one-way analysis of variance and Tukey multiple comparison. ^#P < 0.05 and ^##P < 0.01 vs. control group; *P < 0.05 and **P < 0.01 vs. CYP group.