Table 3.

Affinity of [¹⁹F]FNM for other CNS receptors

Target	Radioligand	Ligand used as positive control	IC50 ± SEM (Homologous inhibition/Positive control) (M)	IC50 ± SEM ([19F]FNM inhibition) (M)
NMDA receptor glycine site	[3H]-glycine	L-glycine	3.5 ± 2.2.10−7	No inhibition
AMPA receptor	[3H]-AMPA	AMPA	2.7 ± 1.7.10−7	No inhibition
Kaïnate receptor	[3H]-kainic acid	Kaïnic acid	6.5 ± 2.5.10−8	No inhibition
Opioïd receptors	[3H]-diprenorphine	Diprenorphine	5.4 ± 2.4.10−10	9.6 ± 2.8 .10−5
µ opioïd receptor	[3H]-DAMGO	DAMGO	9.1 ± 0.8.10−10	1.4 ± 0.2.10−4
Dopaminergic receptor (D1)	[3H]-SCH23390	SCH23390	6.2 ± 2.4.10−9	> 10−3
Dopaminergic receptor (D2)	[3H]-raclopride	Butaclamol	7.6 ± 3.6.10−9	> 10−3