Table 1.
Basal cholesterol levels versus post induction cholesterol levels, and the post-treatment cholesterol levels.
| Groups | Basal Cholesterol (mg/dL) | Post Induction Cholesterol (mg/dL) | Increase in cholesterol levels (%) | (After 14 days treatment) |
||
|---|---|---|---|---|---|---|
| Cholesterol (mg/dL) | LDL-C (mg/dL) | HDL-C (mg/dL) | ||||
| 1 (control) | 2.43 ± 0.18b | 3.11 ± 0.14b | 27.98 | 2.85 ± 0.13a | 0.47 ± 0.02a | 1.89 ± 0.14a |
| 2(Ind) | 2.44 ± 0.20b | 3.43 ± 0.13a | 40.57 | 3.59 ± 0.12b | 0.75 ± 0.15a | 2.27 ± 0.15a |
| 3(Ffb) | 2.50 ± 0.12b | 3.41 ± 0.16a | 36.40 | 2.69 ± 0.13a | 0.38 ± 0.04b | 1.98 ± 0.05a |
| 4 (500 mg/kg) | 2.48 ± 0.26b | 3.46 ± 0.12a | 39.52 | 2.90 ± 0.13a | 0.62 ± 0.13a | 1.93 ± 0.13a |
| 5 (250 mg/kg) | 2.48 ± 0.26b | 3.23 ± 0.27a | 30.24 | 2.56 ± 0.15a | 0.42 ± 0.06a | 1.99 ± 0.06a |
| 6 (100 mg/kg) | 2.47 ± 0.22b | 3.46 ± 0.12a | 40.08 | 2.57 ± 0.13a | 0.18 ± 0.03c | 1.99 ± 0.08a |
Values are means ± SEM of three independent experiment. Values within the same column followed by different letters are significantly different at p < 00.5.
Groups: 1(control) given 2% acacia; 2 (Ind) Induced, not treated; 3 (Ffb) Induced, treated with Fenofibrate (2.29 mg/kg body weight); 4 (500 mg/kg) Induced, treated with 500 mg/kg body weight of extract; 5 (250 mg/kg) Induced, treated with 250 mg/kg body weight of extract; 6 (100 mg/kg) Induced, treated with100 mg/kg body weight of extract. LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol.