Table 4.
Haematological parameters of the Wistar rats post treatment.
Groups | WBC (109/L) | RBC (1012/L) | HGB (g/dL) | HCT (Pcv %) | PLT (109/L) | MCV(fl) | MCH (pg) | MCHC (g/dL) |
---|---|---|---|---|---|---|---|---|
1 (control) | 6.70 ± 0.22a | 6.48 ± 0.43a | 12.78 ± 0.83a | 45.02 ± 3.27a | 474.4 ± 63.66a | 71.66 ± 1.44a | 18.52 ± 0.31a | 26.00 ± 0.60a |
2(Ind) | 7.64 ± 0.21a | 7.65 ± 0.33b | 13.38 ± 0.40a | 51.02 ± 1.58a | 624.2 ± 13.75a | 66.28 ± 1.15a | 17.86 ± 0.34a | 25.78 ± 0.49a |
3(Ffb) | 8.86 ± 0.96b | 6.51 ± 0.25a | 12.28 ± 0.37a | 48.40 ± 1.30a | 705.8 ± 7.55b | 69.32 ± 2.42a | 18.50 ± 0.46a | 26.32 ± 0.38a |
4 (500 mg/kg) | 9.72 ± 0.27c | 6.66 ± 0.22a | 11.82 ± 0.44a | 45.42 ± 1.49a | 791.6 ± 22.24c | 68.90 ± 1.76a | 17.50 ± 0.43a | 26.18 ± 1.02a |
5 (250 mg/kg) | 7.00 ± 0.47a | 7.04 ± 0.10a | 13.00 ± 0.23a | 49.12 ± 1.87a | 624.4 ± 85.56a | 70.24 ± 2.76a | 18.74 ± 0.38a | 26.66 ± 0.84a |
6 (100 mg/kg) | 12.20 ± 0.55d | 7.41 ± 0.22b | 13.70 ± 0.14a | 51.92 ± 0.71a | 647.4 ± 31.78a | 69.68 ± 0.61a | 18.38 ± 0.27a | 26.22 ± 0.34a |
Values are means ± SEM of three independent experiment.
Values within the same column followed by different letters are significantly different at p < 00.5.
Groups: 1(control) given 2% acacia; 2 (Ind) Induced, not treated; 3 (Ffb) Induced, treated with Fenofibrate (2.29 mg/kg body weight); 4 (500 mg/kg) Induced, treated with 500 mg/kg body weight of extract; 5 (250 mg/kg) Induced, treated with 250 mg/kg body weight of extract; 6 (100 mg/kg) Induced, treated with100 mg/kg body weight of extract. WBC = White blood cells, RBC = Red blood cells, HGB = Haemoglobin, HCT = Haematocrit, PLT = Platelets, MCV = Mean Corpuscular Volume, MCH = Mean Corpuscular Haemoglobin and MCHC = Mean Corpuscular Haemoglobin Concentration.