Table 5.
Biochemical Parameters of the Wistar rats post treatment.
Groups | Protein (g/L) | Albumin (g/L) | Urea (mg/L) | Creatinine (umol/L) | ALP(U/L) | AST (U/L) | ALT (U/L) |
---|---|---|---|---|---|---|---|
1 (control) | 82.7 ± 1.51 | 43.7 ± 0.47 | 4.10 ± 0.44 | 82.4 ± 1.93 | 38.0 ± 1.70a | 33.8 ± 0.97 | 13.6 ± 1.50 |
2(Ind) | 81.3 ± 0.69 | 42.5 ± 0.19 | 4.03 ± 0.02 | 79.9 ± 0.83 | 29.4 ± 1.03b | 38.4 ± 3.37 | 16.6 ± 0.40 |
3(Ffb) | 79.3 ± 1.24 | 41.3 ± 0.75 | 3.73 ± 0.32 | 76.3 ± 1.92 | 33.4 ± 2.80a | 31.2 ± 2.65 | 14.0 ± 1.30 |
4 (500 mg/kg) | 79.7 ± 1.34 | 41.9 ± 0.43 | 3.99 ± 0.45 | 79.8 ± 3.02 | 36.4 ± 1.97a | 35.2 ± 6.67 | 14.4 ± 0.93 |
5 (250 mg/kg) | 82.8 ± 1.33 | 41.3 ± 1.40 | 4.27 ± 0.36 | 74.0 ± 4.54 | 37.6 ± 1.63a | 36.2 ± 2.85 | 15.2 ± 1.86 |
6 (100 mg/kg) | 82.9 ± 2.45 | 42.2 ± 0.59 | 4.34 ± 0.07 | 79.1 ± 3.02 | 24.6 ± 0.93c | 38.8 ± 3.40 | 14.4 ± 0.51 |
Values are means ± SEM of three independent experiment.
Values within the same column followed by different letters are significantly different at p < 00.5.
Groups: 1(control) given 2% acacia; 2 (Ind) Induced, not treated; 3 (Ffb) Induced, treated with Fenofibrate (2.29 mg/kg body weight); 4 (500 mg/kg) Induced, treated with 500 mg/kg body weight of extract; 5 (250 mg/kg) Induced, treated with 250 mg/kg body weight of extract; 6 (100 mg/kg) Induced, treated with100 mg/kg body weight of extract. ALP= Alkaline Phosphatase; AST = Aspartate Amino transferase; and ALT = Alanine Amino transferase.