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. 2023 May 12;102(7):891–904. doi: 10.1111/aogs.14570

TABLE 3.

Logistic regression models for the prediction of adverse perinatal outcome prior to 34 weeks, N = 72.

Model 1
CPR MoM + DV PI MoM + EFW centile + maternal age + parity
AUC (95% CI) 0.88 (0.78–0.97)
AIC 61.6 Intercept CPR MoM DV PI MoM EFW centile Maternal age Parity
p‐value <0.0001 p‐value <0.001 NS NS NS NS
NPP (%) 66.7 Estimate 488 185 −503 696 0,21 585 −0,00623 −0,00391 −0,12 940
PPP (%) 88.3 OR 0.006 1.24 0.99 0.97 0.88
Model 2
CPR MoM + DV PI MoM + EFW centile + maternal age
AUC (95% CI) 0.88 (0.79–0.97)
AIC 59.3 Intercept CPR MoM DV PI MoM EFW centile Maternal age
p‐value <0.0001 p‐value <0.001 NS NS NS
NPP (%) 66.7 Estimate 496 640 −507 991 0,20 756 −0,00608 −0,00725
PPP (%) 88.3 OR 0.006 1.23 0.99 0.99
Model 3
CPR MoM + DV PI MoM + EFW centile + parity
AUC (95% CI) 0.88 (0.79–0.97)
AIC 59.2 Intercept CPR MoM DV PI MoM EFW centile Parity
p‐value <0.0001 p‐value <0.001 NS NS NS
NPP (%) 66.7 Estimate 475 573 −504 539 0,21 519 −0,00609 −0,13 400
PPP (%) 88.3 OR 0.006 1.24 0.99 0.87
Model 4
CPR MoM + DV PI MoM + EFW centile
AUC (95% CI) 0.87 (0.78–0.97)
AIC 57 Intercept CPR MoM DV PI MoM EFW centile
p‐value <0.0001 p‐value <0.001 NS NS
NPP (%) 66.7 Estimate 472 989 −509 787 0,20 625 −0,00582
PPP (%) 88.3 OR 0.006 1.23 0.99
Model 5
CPR MoM + DV PI MoM
AUC (95% CI) 0.87 (0.78–0.96)
AIC 55 Intercept CPR MoM DV PI MoM
p‐value <0.0001 p‐value <0.001 NS
NPP (%) 66.7 Estimate 476 576 −528 666 0,21 398
PPP (%) 88.3 OR 0.0051 1.24
Model 6
CPR MoM + EFW centile
AUC (95% CI) 0.88 (0.79–0.97)
AIC 54.8 Intercept CPR MoM EFW centile
p‐value <0.0001 p‐value <0.001 NS
NPP (%) 66.7 Estimate 499 560 −512 469 −0,00588
PPP (%) 88.3 OR 0.006 0.99
Model 7
DV PI MoM + EFW centile
AUC (95% CI) 0.68 (0.51–0.85)
AIC 73.7 Intercept DV PI MoM EFW centile
p‐value <0.05 p‐value NS <0.05
NPP (%) 50 Estimate 0,88 690 0,58 415 −0,02291
PPP (%) 81 OR 1.79 0.98
Model 8
DV PI MoM
AUC (95% CI) 0.56 (0.40–0.71)
AIC 76.2 Intercept DV PI MoM
p‐value NS p‐value NS
NPP (%) Estimate 0,53 629 0,63 787
PPP (%) 79.2 OR 1.89
Model 9
EFW centile
AUC (95% CI) 0.83 (0.72–0.94)
AIC 72.7 Intercept EFW centile
p‐value <0.0001 p‐value <0.05
NPP (%) 50 Estimate 162 739 −0,02391
PPP (%) 81 OR 0.98
Model 10
CPR MoM
AUC (95% CI) 0.88 (0.79–0.97)
AIC 52.9 Intercept CPR MoM
p‐value <0.0001 p‐value <0.0001
NPP (%) 66.7 Estimate 503 977 −531 471
PPP (%) 88.3 OR 0.0049
Model 11
CPR MoM + EFW centile + parity
AUC (95% CI) 0.88 (0.79–0.97)
AIC 57 Intercept CPR MoM EFW centile Parity
p‐value <0.0001 p‐value <0.001 NS NS
NPP (%) 61.5 Estimate 502 893 −507 038 −0,00616 −0,13 068
PPP (%) 88.1 OR 0.0063 0.99 0.88

Abbreviations: AIC, Akaike information criteria; AUC, area under the curve; CPR MoM, cerebroplacental ratio multiples of the median; DV MoM, ductus venosus pulsatility index multiples of the median; EFW, estimated fetal weight; GA at delivery, gestational age at delivery; NPP, negative predictive power; OR, odds ratio; PPP, positive predictive power.