Fig. 2.

Fabrication of three-dimensional (3D) interconnected bioceramic scaffolds using extrusion-microdrilling [120]. (A) Schematic diagram of manufacturing bioceramic scaffold and its effect in vivo and in vitro. (B) a) Schematic diagram of the extrusion-microdrilling process for preparing 3D interconnected green bodies. b) Digital photographs of the extrusion-microdrilling samples. c) Schematic diagram of the configuration of extruded pores and microdrilled pores in the extrusion-microdrilling samples. (C) X-ray diffraction (XRD) patterns. (D) Photographs of Masson's trichrome staining in femoral defects implanted with E-TCP, EM-TCP, and EM-TCP/SrPG scaffolds at the 6th week postoperatively.