Table 5.
Predictors of Time to Overall Survival in Patients with Adult-Type Diffuse Glioma
| Variables | N (%) | Overall Survival | ||
|---|---|---|---|---|
| Median (Months) | p-Value (Log-rank) | |||
| Age | ≤44 Years | 24 (53.33) | 31 | 0.01 |
| >44 Years | 21 (46.67) | 12 | ||
| Gender | Male | 36 (80.00) | 22 | 0.332 |
| Female | 09 (20.00 | 15 | ||
| Karnofsky Performance Score |
70 | 15 (33.33) | 10 | 0.001 |
| 80 | 16 (35.56) | 17 | ||
| 90 | 14 (31.11) | - | ||
| Excision | GTE | 36 (80.00) | 22 | 0.429 |
| PE/Biopsy | 09 (20.00) | 14 | ||
| WHO CNS 2021 Type | Astrocytoma IDH-mutant | 11 (24.44) | - | 0.002 |
| Oligodendroglioma IDH-mutant 1p19q Deleted | 10 (22.22) | 24 | ||
| Glioblastoma IDH-wildtype | 24 (53.33) | 12 | ||
| WHO CNS 2021 Grade | 2 | 13 (28.89) | - | 0.001 |
| 3 | 07 (15.55) | 31 | ||
| 4 | 25 (55.55) | 13 | ||
| IHC-IDH | Mutant | 21 (46.67) | - | 0.000 |
| Wildtype | 24 (53.33) | 12 | ||
| CAST-PCR-IDH | Mutant | 26 (57.78) | 31 | 0.003 |
| Wildtype | 19 (42.22) | 12 | ||
GTE, Gross Total Excision; PE, Partial Excision; RANO, Response Assessment in Neuro-Oncology; IDH1, Isocitrate Dehydrogenase- 1