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. 2020 Dec 13;79(4):451–457. doi: 10.1016/j.mjafi.2020.09.014

Table 6.

BDNF level improvement of cases (N = 60) after treatment with respect to severity of depression.

Depression Severity BDNF (before treatment) (ng/ml)
BDNF (after treatment) (ng/ml)
p-value within the group
Mean SD Mean SD
Mild (n = 15) 19.42 8.9 20.64 9.86 0.172
Moderate (n = 15) 27.16 10.22 34.7 26.75 0.172
Severe (n = 15) 12.91 3.15 19.63 12.54 0.006∗#
Very severe (n = 15) 14.74 6.64 14.19 3.15 0.733
p-value 0.001∗ 0.003∗

∗Significant (p-value < 0.05). The Kruskal-Wallis test is used.

∗#Significant (p-value < 0.05). The Wilcoxon signed-rank test is used.

BDNF, brain-derived neurotrophic factor.