Skip to main content
. 2023 Apr 7;14(4):637–651. doi: 10.1016/j.advnut.2023.04.002

TABLE 2.

The results of subgroup analyses according to key participant and study characteristics

Subgroup category Subgroup Systolic blood pressure
Diastolic blood pressure
No. of studies No. of participants Effect estimate MD (95% CI) (mm Hg) Test for subgroup differences No. of studies No. of participants Effect estimate MD (95% CI) (mm Hg) Test for subgroup differences
Study design Parallel 11 928 −1.63 (−3.40, 0.14) χ2 = 3.17, df = 1; (P = 0.07), I2 = 68.5% 10 888 −0.63 (−1.25, 0.00) χ2 = 2.54, df = 1; (P = 0.11), I2 = 60.6%
Crossover 5 362 1.51 (−1.46, 4.48) 5 362 0.94 (−0.88, 2.77)
Study blinding With blinding 5 402 −0.08 (−1.88, 1.71) χ2 = 1.61, df = 1; (P = 0.20), I2 = 37.8% 5 402 −0.63 (−2.18, 0.93) χ2 = 0.60, df = 1; (P = 0.44), I2 = 0%
Without blinding 11 888 −1.92 (−4.11, 0.27) 10 848 0.09 (−0.84, 1.03)
Study duration (wk) 1–4 1 40 0.10 (−8.82, 9.02) χ2 = 0.14, df = 3; (P = 0.99), I2 = 0% 1 40 −1.10 (−5.99, 3.79) χ2 = 4.89, df = 3; (P = 0.18), I2 = 38.6%
5–8 9 487 −1.28 (−4.75, 2.19) 8 447 0.97 (−0.69, 2.63)
9–16 5 670 −0.98 (−3.42, 1.45) 5 670 −0.20 (−1.17, 0.78)
>16 1 93 −1.30 (−2.36, 0.24) 1 93 −1.00 (−1.81, −0.19)
Sample size n < 50 9 353 −1.76 (−5.32, 1.80) χ2 = 0.18, df = 1; (P = 0.67), I2 = 0% 8 313 −0.03 (−2.03, 1.98) χ2 = 0.07, df = 1; (P = 0.79), I2 = 0%
n ≥ 50 7 937 −0.91 (−2.51, 0.69) 7 937 −0.32 (−1.23, 0.59)
Participant sex Males and females 11 1023 −1.52 (−2.75, −0.29) χ2 = 0.48, df = 2; (P = 0.79), I2 = 0% 10 983 −0.24 (−0.96, 0.49) χ2 = 1.72, df = 2; (P = 0.42), I2 = 0%
Females only 3 209 −2.47 (−10.32, 5.38) 3 209 −1.67 (−3.74, 0.40)
Males only 2 58 0.44 (−5.40, 6.29) 2 58 0.23 (−3.74, 4.20)
Participant age <40 y 3 135 −3.72 (−13.59, 6.16) χ2 = 0.29, df = 2; (P = 0.86), I2 = 0% 3 135 −2.49 (−5.07, 0.10) χ2 = 7.54, df = 2; (P = 0.02), I2 = 73.5%
≥40 y 8 860 −0.98 (−2.97, 1.00) 8 860 0.47 (−0.47, 1.41)
Mixed ages 5 295 −1.21 (−2.22, −0.19) 4 255 −0.93 (−1.70, −0.16)
BMI status Overweight/obese 9 703 −2.79 (−4.68, −0.90) χ2 = 10.15, df = 1; (P = 0.001), I2 = 90.1% 8 663 −0.56 (−1.20, 0.09) χ2 = 0.19, df = 1; (P = 0.67), I2 = 0%
Mixed BMI 7 587 1.56 (−0.34, 3.45) 7 587 −0.19 (−1.72, 1.34)
Diabetes status With diabetes 5 560 −1.00 (−3.85, 1.85) χ2 = 0.11, df = 2; (P = 0.95), I2 = 0% 5 560 −0.13 (−1.50, 1.24) χ2 = 0.46, df = 2; (P = 0.79), I2 = 0%
Without diabetes 6 369 −1.39 (−2.39, −0.38) 6 369 −0.65 (−1.34, 0.04)
Unspecified 5 361 −1.90 (−6.95, 3.15) 4 321 −0.38 (−3.22, 2.46)
Legume type Lupin, flour 3 201 −1.57 (−2.81, −0.34) χ2 = 0.34, df = 1; (P = 0.56), I2 = 0% 3 201 −0.46 (−1.64, 0.72) χ2 = 0.21, df = 1; (P = 0.65), I2 = 0%
Mixed, whole 13 1089 −0.82 (−3.04, 1.39) 12 1049 −0.10 (−1.09, 0.88)
Legume dose, weekly (g) ≤450 4 232 −1.15 (−2.18, −0.11) χ2 = 1.17, df = 2; (P = 0.56), I2 = 0% 4 232 −0.91 (−1.70, −0.11) χ2 = 2.66, df = 2; (P = 0.26), I2 = 24.8%
>450 to <1000 8 668 −2.26 (−4.00, −0.52) 7 628 0.14 (−0.85, 1.14)
≥1000 g 4 390 −1.36 (−6.27, 3.55) 4 390 −0.79 (−3.37, 1.79)
Intake frequency 1–4 d/wk 5 205 0.14 (−3.31, 3.59) χ2 = 0.51, df = 1; (P = 0.47), I2 = 0% 5 205 1.05 (−1.55, 3.66) χ2 = 1.22, df = 1; (P = 0.27), I2 = 17.8%
≥5 d/wk 11 1085 −1.27 (−3.04, 0.49) 10 1045 −0.47 (−1.18, 0.24)
Dietary feature Hypocaloric 6 515 −3.61 (−6.43, −0.79) χ2 = 5.02, df = 1; (P = 0.03), I2 = 80.1% 5 575 −0.84 (−1.56, −0.12) χ2 = 2.83, df = 1; (P = 0.09), I2 = 64.6%
Usual diet 10 775 0.03 (−1.45, 1.50) 10 775 0.21 (−0.78, 1.19)