Table 1.
Baseline characteristics.
| Variable | OAC− (n = 398) | OAC+ (n = 198) | Overall | p |
|---|---|---|---|---|
| Age | 80.6 (74.1–86.4) | 82.5 (76.5–86.9) | 81.4 (74.7–86.7) | 0.05 |
| Male | 201 (50.5) | 103 (52.0) | 304 (51.0) | 0.73 |
| Hypertension | 286 (71.9) | 168 (84.9) | 454 (76.2) | <0.001 |
| History of vascular disease | 68 (17.1) | 52 (26.3) | 120 (20.1) | 0.008 |
| Diabetes mellitus | 89 (22.4) | 54 (27.3) | 143 (24.0) | 0.19 |
| CCF | 69 (17.3) | 48 (24.2) | 117 (19.6) | 0.05 |
| Hyperlipidaemia | 230 (57.8) | 135 (68.2) | 365 (61.2) | 0.01 |
| Smoking | 140 (35.2) | 76 (38.4) | 216 (36.2) | 0.44 |
| Systolic BP (n = 474) | 131 (120–143) | 135 (120–147) | 133 (120–144) | 0.10 |
| Diastolic BP (n = 474) | 72 (65–78) | 71 (66–78) | 71 (65–78) | 0.84 |
| Previous stroke/TIA or systemic embolism | 99 (24.9) | 96 (48.5) | 195 (32.7) | <0.001 |
| CHA2DS2-VASC | 4 (3–5) | 5 (4–6) | 4 (3–5) | <0.001 |
| Known AF | 180 (45.2) | 196 (99.0) | 376 (63.1) | <0.001 |
| NIHSS (n = 524) | 6 (3–12) | 6 (2.5–11) | 6 (3–12) | 0.46 |
| Lacunar syndrome | 66 (16.6) | 51 (25.8) | 117 (19.6) | 0.008 |
| MRI | 117 (29.4) | 57 (28.8) | 174 (29.2) | 0.88 |
| Any acute infarct | 346 (86.9) | 161 (81.3) | 507 (85.1) | 0.07 |
| Any proximal large artery atheroma (n = 589) | 284 (72.3) | 158 (80.6) | 442 (75.0) | 0.03 |
| Any contralateral atheroma (n = 521) | 244 (70.3) | 137 (78.7) | 381 (73.1) | 0.04 |
| Contralateral large artery atheroma ⩾50% (n = 521) | 30 (8.7) | 19 (10.9) | 49 (9.4) | 0.40 |
| Proximal large artery atheroma ⩾50% (n = 589) | 45 (11.5) | 36 (18.4) | 81 (13.8) | 0.02 |
| Other high risk cardiac mechanism | 19 (4.8) | 17 (8.6) | 36 (6.0) | 0.07 |
| Small vessel occlusion | 18 (4.5) | 17 (8.6) | 35 (5.9) | 0.05 |
| Plasma CRP (mg/l) (n = 505) | 5 (2–16) | 7 (2–22) | 6 (2–18) | 0.17 |
| Serum creatinine (mmol/l) (n = 589) | 82 (68–99) | 85 (67–104) | 82.6 (67.6–102) | 0.43 |
| LA area (n = 251) | 24.1 (20.4–27.7) | 26.4 (21.1–31.1) | 24.9 (20.4–29.9) | 0.006 |
| LA volume (ml/m2) (n = 179) | 43.2 (34.7–52.7) | 47.0 (38.2–62.0) | 45.2 (36.5–57.5) | 0.07 |
| Any RWMA (n = 252) | 30 (19.6) | 18 (18.2) | 48 (19.1) | 0.78 |
| Severe LV impairment (n = 258) | 21 (13.5) | 12 (11.8) | 33 (12.8) | 0.69 |
Categorical data is presented as number of observations (%). Skewed data is presented as median (IQR). There were 596 observations for each variable unless otherwise stated.