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. 2023 Jun 27;13:1110235. doi: 10.3389/fonc.2023.1110235

Table 1.

Overview of the preferred derivatization reagents used in SCFAs analysis.

Matrix Derivatization agent Molecule Method Reference
Feces DHPP graphic file with name fonc-13-1110235-i001.jpg LC-MS/MS (131)
AMQ graphic file with name fonc-13-1110235-i002.jpg LC-MS/MS (126)
AABD-SH graphic file with name fonc-13-1110235-i003.jpg LC-MS/MS (132)
BP graphic file with name fonc-13-1110235-i004.jpg LC-MS/MS (133)
3-NPH graphic file with name fonc-13-1110235-i005.jpg LC-MS/MS (134)
2-PA graphic file with name fonc-13-1110235-i006.jpg LC-MS/MS (135)
GT graphic file with name fonc-13-1110235-i007.jpg LC-MS/MS (132)
PCF graphic file with name fonc-13-1110235-i008.jpg GC-MS (136)
BSTFA graphic file with name fonc-13-1110235-i009.jpg GC-MS (47, 137)
i-Bu graphic file with name fonc-13-1110235-i010.jpg GC-MS (138)
Serum DHPP graphic file with name fonc-13-1110235-i011.jpg LC-MS/MS (131)
2-NPH graphic file with name fonc-13-1110235-i012.jpg LC-MS/MS (139)
DIAAA graphic file with name fonc-13-1110235-i013.jpg LC-MS/MS (140)
Plasma AABD-SH graphic file with name fonc-13-1110235-i014.jpg LC-MS/MS (132)
O-BHA graphic file with name fonc-13-1110235-i015.jpg LC-MS/MS (132, 141)
BP graphic file with name fonc-13-1110235-i016.jpg LC-MS/MS (133)
BSTFA graphic file with name fonc-13-1110235-i017.jpg GC-MS (47, 137)
Urine O-BHA graphic file with name fonc-13-1110235-i018.jpg LC-MS/MS (141, 142)
BSTFA graphic file with name fonc-13-1110235-i019.jpg GC-MS (47, 137)

2-NPH, 2-nitrophenylhydrazine; 3-NPH, 3-nitrophenylhydrazine; 2-PA, 2-picolylamine; AABD-SH, 4-acetamido-7-mercapto-2,1,3-benzoxadiazole; AMQ, 4-aminomethylquinoline; BP, 2-bromoacetophenone; BSTFA, N,O-bis(trimethylsilyl)trifluoroacetamide; DHPP, N,N-dimethyl-6,7-dihydro-5H-pyrrolo [3,4-d] pyrimidine-2-amine; DIAAA, 5-(diisopropylamino)amylamine; GT, Girard´s reagent T (trimethylaminoacetohydrazide chloride); i-Bu, isobutyl chloroformate; O-BHA, O-benzylhydroxylamine; PCF, propyl-chloroformate.