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. 2018 Jun 6;13(10):1139–1155. doi: 10.2217/nnm-2017-0337

Table 2.  . Antifungal activity of free ebselen and ebselen-loaded in core-shell nanocapsules against Candida species.

Candida species MIC (μg/ml)

  Free ebselen Ebselen in Eb-NCS 3
Candida tropicalis 1.520 0.375

Candida albicans 0.190 0.094

Candida glabrata 0.024 0.094

Candida parapsilosis 0.015 0.012

No growth inhibition of any Candida species was observed for Ebselen-free nanocapsules.

Eb-NC: Ebselen-loaded core-shell nanocapsule; MIC: Minimal inhibitory concentration (the lowest concetration of the tested antifungals that inhibited the visible growth of Candida cells after overnight incubation).