ADP-induced changes in GP IIb/IIIa (PAC-1 antibody staining) and P-selectin surface expression in washed human platelets pre-incubated with vehicle (saline, blue) or the indicated concentrations of either 1,5-AHG (green, panel A) or glucose (green, panel B). Bars represent means (±SD), Two-sided P values were calculated by Kruskal–Wallis test with Dunn’s post hoc test for multiple-group comparisons. Numbers of independent biological replicates (n) are indicated.