Table 2.
Demographic Characteristics of Adults Hospitalized With Acute Respiratory Illness
| Variable | RSV (n = 328) | FluA (n = 2155) | FluB (n = 606) | Other Respiratory Viruses (n = 596) | Negative for Respiratory Viruses (n = 3900) | P Value |
|---|---|---|---|---|---|---|
| Age, y, median (IQR) | 74.9 (65–85) | 75.9 (66–86) | 76.2 (66–86) | 74.7 (65–85) | 74.0 (65–83) | <.001 |
| Age category, y | ||||||
| 50–59 | 11.6 (38/328) | 13.4 (289/2155) | 12.7 (77/606) | 12.9 (77/596) | 14.1 (550/3900) | <.001 |
| 60–64 | 12.5 (41/328) | 8.4 (180/2155) | 8.4 (51/606) | 10.6 (63/596) | 10.3 (400/3900) | |
| 65– 69 | 11.9 (39/328) | 10.1 (218/2155) | 11.1 (67/606) | 11.2 (67/596) | 11.1 (431/3900) | |
| 70–79 | 24.4 (80/328) | 23.6 (509/2155) | 20.5 (124/606) | 26.3 (157/596) | 27.6 (1076/3900) | |
| ≥80 | 39.6 (130/328) | 44.5 (959/2155) | 47.4 (287/606) | 38.9 (232/596) | 37.0 (1443/3900) | |
| Sex, male | 36.3 (119/328) | 48.7 (1050/2155) | 44.1 (267/606) | 45.5 (271/596) | 48.5 (1893/3900) | <.001 |
| Past or current smoker | 54.4 (174/320) | 52.5 (1103/2098) | 44.2 (259/586) | 62.8 (367/584) | 68.7 (2633/3833) | <.001 |
| BMI, kg/m2, median (IQR) | 26.4 (22.2–31.9) | 25.9 (22.8–30.1) | 25.9 (22.1–30.0) | 26.0 (22.2–30.5) | 25.8 (21.9–30.7) | .156 |
| BMI category (kg/m2) | ||||||
| Underweight (<18.5) | 6.2 (19/306) | 4.6 (89/1929) | 7.2 (38/525) | 6.3 (36/567) | 8.1 (297/3296) | <.001 |
| Normal weight (18.5–24.9) | 36.3 (111/306) | 37.2 (718/1929) | 37.5 (197/525) | 36.7 (208/567) | 36.9 (1348/3296) | |
| Overweight (25.0–29.9) | 26.5 (81/306) | 32.5 (626/1929) | 30.1 (158/525) | 29.3 (166/567) | 27.1 (992/3296) | |
| Obese (30.0–40.0) | 22.5 (69/306) | 22.5 (434/1929) | 20.4 (107/525) | 22.6 (128/567) | 22.1 (807/3296) | |
| Very obese (>40.0) | 8.5 (26/306) | 3.2 (62/1929) | 4.8 (25/525) | 5.1 (29/567) | 5.7 (210/3296) | |
| Admitted from LTC | 8.8 (29/328) | 9.1 (195/2152) | 11.1 (67/604) | 7.7 (46/595) | 7.6 (295/3895) | .028 |
| Influenza immunization | 67.7 (212/313) | 58.5 (1197/2046) | 59.6 (359/602) | 69.5 (397/571) | 66.6 (2484/3729) | <.001 |
| Immunocompromise | 26.8 (88/328) | 27.2 (586/2155) | 28.7 (174/606) | 29.2 (174/596) | 27.3 (1065/3900) | .817 |
| ≥1 comorbidity | 98.1 (322/328) | 94.7 (2040/2155) | 94.5 (573/606) | 98.0 (583/595) | 95.9 (3739/3900) | <.001 |
| Vascular | 71.3 (234/328) | 71.2 (1534/2155) | 71.8 (435/606) | 69.8 (416/596) | 68.7 (2678/3900) | .212 |
| Cardiac | 55.5 (182/328) | 46.4 (999/2155) | 45.2 (274/606) | 51.8 (309/596) | 51.5 (2009/3900) | <.001 |
| Pulmonary | 48.2 (158/328) | 38.3 (826/2155) | 30.4 (184/606) | 46.3 (276/596) | 55.2 (2154/3900) | <.001 |
| Renal | 48.2 (158/328) | 38.3 (826/2155) | 30.4 (184/606) | 46.3 (276/596) | 55.2 (2154/3900) | .510 |
| Endocrine | 33.2 (109/328) | 34.6 (746/2155) | 31.7 (192/606) | 31.3 (186/595) | 30.8 (1200/3900) | .109 |
| Diabetes mellitus, uncomplicated | 6.4 (21/328) | 5.2 (112/2155) | 5.3 (32/606) | 4.0 (24/595) | 5.0 (194/3900) | |
| Diabetes mellitus, complicated | 25.0 (82/328) | 29.4 (634/2155) | 26.4 (160/606) | 27.2 (162/595) | 25.8 (1006/3900) | |
| Neuromuscular | 7.0 (23/328) | 9.1 (197/2155) | 10.1 (61/606) | 8.2 (49/596) | 6.8 (266/3900) | .004 |
| Rheumatologic | 3.7 (12/328) | 4.3 (93/2155) | 3.8 (23/606) | 4.2 (25/596) | 4.1 (160/3900) | .968 |
| Gastrointestinal | 2.1 (7/328) | 3.1 (66/2155) | 3.5 (21/606) | 1.2 (7/596) | 1.9 (76/3900) | .151 |
| Hepatic | 0.9 (3/328) | 1.8 (38/2155) | 1.6 (16/606) | 2.0 (12/596) | 1.7 (67/3900) | .379 |
| Other chronic illnesses | 12.2 (40/328) | 19.4 (417/2155) | 20.8 (126/606) | 13.8 (82/596) | 13.0 (508/3900) | <.001 |
| No. of medications prior to admission | ||||||
| 0–4 | 19.0 (62/326) | 28.8 (614/2134) | 30.0 (179/596) | 20.8 (122/587) | 22.5 (870/3872) | <.001 |
| 5–7 | 30.1 (98/326) | 28.7 (612/2134) | 27.9 (166/596) | 27.3 (160/587) | 24.6 (951/3872) | |
| 8–10 | 22.7 (74/326) | 23.2 (495/2134) | 23.8 (142/596) | 27.3 (160/587) | 23.6 (913/3872) | |
| 11–13 | 13.8 (45/326) | 10.8 (231/2134) | 10.1 (60/596) | 11.4 (67/587) | 15.0 (580/3872) | |
| 14–16 | 8.3 (27/326) | 5.5 (118/2134) | 5.4 (32/596) | 8.3 (49/587) | 8.5 (328/3872) | |
| >16 | 6.1 (20/326) | 3.0 (64/2134) | 2.9 (17/596) | 4.9 (29/587) | 5.9 (230/3872) |
Data are presented as % (no./No.) unless otherwise indicated. Coinfections were excluded to compare patient demographics between viruses.
Abbreviations: BMI, body mass index; FluA, influenza A; FluB, influenza B; IQR, interquartile range; LTC, long-term care; RSV, respiratory syncytial virus.