Table 1.
Baseline characteristics, separately for men and women
| Variable | Men (n = 4095) | Women (n = 5389) | Missing data (n men/n women) |
|---|---|---|---|
| Age, yr (n = 4095; n = 5389) | 64.7 ± 9.4 | 65.6 ± 10.2 | 0/0 |
| Body mass index, kg/m2 (n = 4060; n = 5288) | 27.0 ± 3.6 | 27.4 ± 4.6 | 35/101 |
| Systolic blood pressure, mm Hg (n = 4082; n = 5348) | 141 ± 20 | 139 ± 22 | 13/41 |
| Diastolic blood pressure, mm Hg (n = 4082; n = 5348) | 80 ± 12 | 78 ± 11 | 13/41 |
| Hypertension, n (valid%) (n = 4029; n = 5264) | 2106 (52.3) | 2529 (48.0) | 66/125 |
| Diabetes mellitus, n (%) (n = 4095; n = 5389) | 599 (14.6) | 559 (10.4) | 0/0 |
| History of CVD, n (valid%) (n = 4068; n = 5365) | 628 (15.4) | 303 (5.6) | 27/24 |
| Smoking (n = 4069; n = 5316) | 26/73 | ||
| Current smoking, n (valid%) | 813 (20.0) | 1005 (18.9) | |
| Past smoking, n (valid%) | 2451 (60.2) | 2050 (38.6) | |
| Never smoking, n (valid%) | 805 (19.8) | 2261 (42.5) | |
| Alcohol use, g/d (n = 3274; n = 4461) | 8.6 (1.6–20.0) | 1.6 (0.3–8.6) | |
| eGFR creatinine, ml/min per 1.73 m2 (n = 4095; n = 5389) | 80 ± 15 | 79 ± 15 | 0/0 |
| eGFR cystatin C, ml/min per 1.73 m2 (n = 4095; n = 5389) | 78 ± 19 | 76 ± 19 | 0/0 |
| Serum cholesterol, mmol/l (n = 4085; n = 5341) | 5.5 ± 1.0 | 5.9 ± 1.0 | 10/48 |
| Serum TSH, mU/l (n = 4095; n = 5387) | 2.18 ± 2.85 | 2.60 ± 3.49 | 0/2 |
| Serum CRP, mg/l (n = 2533; n = 3190) | 2.4 ± 4.7 | 2.6 ± 4.4 | 1562/2199 |
| Serum SHBG, nmol/l (n = 4095; n = 5389) | 47.7 ± 20.2 | 67.2 ± 34.1 | 0/0 |
| Serum testosterone, nmol/l (n = 4095; n = 5389) | 17.2 ± 6.0 | 0.9 ± 0.8 | 0/0 |
| Serum free testosteronea, nmol/l (n = 4095; n = 5389) | 0.29 ± 0.09 | 0.01 ± 0.01 | 0/0 |
| Skeletal muscle index (n = 2436; n = 3346) | 8.35 ± 0.85 | 6.62 ± 0.70 | 1659/2043 |
CRP, C-reactive protein; CVD, cardiovascular disease; eGFR, estimated glomular filtration rate; n, number; SHBG, sex-hormone binding globulin; TSH, thyroid-stimulating hormone.
Data are presented as number (%), number (valid%), mean ± SD, or median (interquartile range). Values are shown for nonimputed data. For variables with missing data, valid % is given. Number of complete observations is represented by n, for men and women, respectively.
a
Calculated using serum total testosterone, serum SHBG, and constant serum albumin of 4.3 g/dl.