Table 11. Adjuvant chemoradiotherapy stratification treatment recommendations for stage II−III rectal cancer.
Risk stratification for recurrence of stage II−III rectal cancer | Treatments | Recommended level |
TME, total mesorectal excision; CRM, circumferential resection margin; MRF, mesorectal fascia. | ||
Meeting any of the following criteria: T3−4N0 low; CRM+; pN+; Tumor deposits (TDs) Nerve invasion + poor quality of TME operation/mesenteric defects/the quality of TME operation could not be evaluated |
Postoperative concurrent chemoradiotherapy | Recommended |
Meeting all the following criteria: T3−4aN0 if middle or high; CRM−; pN0; |
Postoperative concurrent chemoradiotherapy | Not suggested |
Nerve invasion−; Good quality of TME operation/smooth and intact mesentery |