Table 8. Structural report of surgical resection specimens of colorectum.

Name　　　　　　　　　Sex　　　　　 　　Age　　　　　　　Pathology number Medical record number 　　　　　　　　　　Inspection site
American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) Colorectal Cancer TNM Staging System (8th Edition, 2017) Primary tumor (T) 　Tx　Primary tumor cannot be evaluated 　T0　No evidence of primary tumor 　Tis　Carcinoma in situ: intramucosal carcinoma (invades lamina propria, but without penetrating the muscularis mucosae) 　T1　Tumor invades submucosa 　T2　Tumor invades muscularis propria 　T3　Tumor invades through muscularis propria into pericolorectal tissues 　T4　Tumor invades the visceral peritoneum or invades/adheres to adjacent organs or structures 　　T4a　Tumor penetrates the visceral peritoneum (including tumor perforation of the gross intestine and continuous infiltration of 　　the tumor through the inflammatory region) 　　T4b　Tumor directly invades or adheres to adjacent organs or structures Regional lymph nodes (N) 　Nx　Regional lymph node invaluable 　N0　No regional lymph node metastasis 　N1　Metastasis in 1−3 regional lymph nodes (intra-node tumors ≥0.2 mm) or any number of tumor deposits and no metastasis of 　all identifiable lymph nodes 　　N1a Metastasis in 1 regional lymph node 　　N1b　Metastasis in 2−3 regional lymph node 　　N1c　There is no regional lymph node metastasis, but there are tumor deposits in the following areas: Subserous, mesenteric 　　or pericolic/rectal mesenteric tissue without peritoneum coverage 　N2　Metastasis in 4 or more regional lymph nodes 　　N2a　Metastasis in 4−6 regional lymph nodes 　　N2b　Metastasis in 7 or more regional lymph nodes Metastasis (M) 　M0　No distant metastasis 　M1　Metastasis confined to one or more distant sites or organs, or peritoneal metastasis confirmed 　　M1a　Metastasis in one site or organ without peritoneal metastasis 　　M1b　Metastasis in two or more sites or organs without peritoneal metastasis 　　M1c　Metastasis only in the peritoneal surface or along with other sites or organs
Specimen size	Length: _____ cm Circumference: _____ cm
Tumor location	To the proximal end _____ cm, to the distal end _____ cm
General type	□ Bulge type □ Ulcer type □ Invasive type
Tumor size	Maximum diameter: _____ cm Other two diameters: _____ cm × _____ cm
Perforation of tumor	□ Visible □ Invisible □ Uncertain
Histological classification	□ Adenocarcinoma, non-special type □ Serrated adenocarcinoma □ Adenoma-like adenocarcinoma □ Micropapillary carcinoma □ Mucinous adenocarcinoma □ Poorly cohesive carcinoma □ Signet ring cell carcinoma □ Medullary carcinoma □ Adenosquamous carcinoma □ Undifferentiated carcinoma, non-special type □ Carcinoma with sarcomatoid component
Histological grade	□ Uncertain □ Low level (well/moderately differentiated) □ High level (poorly differentiated, undifferentiated)
Tumor invasion (deepest point)	□ Cannot be assessed □ No evidence of primary tumor □ No membrane propria infiltration □ Intramucosal carcinoma, invasion of the membrane propria/muscularis mucosae □ Tumor invades submucosal layer □ Tumor invades the muscularis propria □ Tumor penetrates the muscularis propria to subserosal adipose tissue or pericolic/perirectal soft tissue □ Tumor penetrates the visceral peritoneum (serous membrane) (including tumor perforation of the gross intestine and continuous infiltration of the tumor through the inflammatory region) □ Adhesion of tumor to other organs or structures: □ Tumors directly invade nearby structures:
Proximal resection margin	□ Cannot be assessed □ No intradermal tumor and dysplasia □ Adenoma (low-grade intraepithelial neoplasia/dysplasia) □ High-grade intraepithelial neoplasia/dysplasia or intramucosal carcinoma □ Invasive cancer involvement
Distal resection margin	□ Cannot be assessed □ No intradermal tumor and dysplasia □ Adenoma (low-grade intraepithelial neoplasia/dysplasia) □ High-grade intraepithelial neoplasia/dysplasia or intramucosal carcinoma □ Invasive cancer involvement
Circumferential (radial) or mesangial margin	□ Inapplicable □ Cannot be assessed □ Non-invasive cancer □ Invasive carcinoma (distance between tumor and resection margin less than 1 mm)
Therapeutic effects (for cancer after neoadjuvant treatment)	□ No pre-treatment □ Therapeutic effect □ No residual tumor (grade 0, complete response) □ Moderate response (grade 1, minor residual tumor) □ Minimal response (grade 2) □ No certain response (grade 3, poor response) □ Uncertain
Tumor budding	□ Low (visual field of 0−4/20 times) □ Medium (visual field of 5−9/20 times) □ High (visual field of 10 or more/20 times) □ Cannot be assessed
Vascular invasion	□ Invisible □ Microvascular invasion □ Lymphatic invasion □ Venous invasion □ Uncertain
Nerve invasion	□ Invisible □ Visible □ Uncertain
Lymph node	□ No lymph nodes submitted or no lymph nodes found □ No. of lymph nodes examined _____ □ No. of lymph nodes involved _____
Extranodal tumor deposits	□ Invisible □ Visible (Number: _____) □ Uncertain
Immunohistochemistry of mismatch repair protein	MLH1 (　) PMS2 (　) MSH2 (　) MSH6 (　)
Pathological stage	□ m (multiple primary tumors) □ r (relapse) □ y (after neoadjuvant treatment) T ___ N ___ M ___