Table 2.
Univariate and multivariate Cox proportional hazards analysis of IL4I1 expression
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Gender (Male vs. Female) | 510 | 1.694 (0.975–2.945) | 0.062 | 1.390 (0.767–2.519) | 0.278 |
| Age (> 45 vs. < = 45) | 510 | 1.593 (0.920–2.758) | 0.096 | 1.558 (0.856–2.835) | 0.147 |
| T stage (T3&T4 vs. T1&T2) | 508 | 2.450 (1.417–4.236) | 0.001* | 2.134 (0.925–4.925) | 0.076 |
| N stage (N1 vs. N0) | 460 | 1.658 (0.936–2.934) | 0.083 | 1.267 (0.685–2.344) | 0.450 |
| Extrathyroidal extension (Yes vs. No) | 492 | 1.874 (1.092–3.216) | 0.023* | 0.867 (0.385–1.955) | 0.731 |
| Primary neoplasm focus type (Multifocal vs. Unifocal) | 500 | 1.025 (0.595–1.764) | 0.929 | / | / |
| IL4I1 (High vs. Low) | 510 | 1.894 (1.083–3.310) | 0.025* | 1.568 (0.860–2.860) | 0.142 |
*p < 0.05