Table 2:

Standard membrane feeding assay using monoclonals purified from serum-free hybridoma media using Protein G.

Immuno-blot	Sample name	IgG conc [µg/ml]	% Uninfect	Oocyst		% Inhibition
				Range	Ave	Estimate	95% CI Lo	95% CI Hi	p-valu e
	Human serum	0	0	16–90	56.1
Pfs25	4B7	93.8	5	0–19	5.4	90.5	72.1	96.8	0.001
Neg Ctrl	F2 03G2 1A12	375.0	5	0–123	43.8
Pfs230	F3 09F4 5E1	375.0	100	0	0.0	100.0	99.7	100.0	0.001
	F5 6D11 7E5	375.0	80	0–2	0.3	99.4	97.4	100.0	0.001
	F5 05A6 2F5	90.0	25	0–33	8.0	81.7	52.1	93.8	0.003
Pfs48/45	F2 14E5 1G9	375.0	10	0–29	5.6	87.3	63.8	95.7	0.001
Pfs25	F5 04F5 2C7	375.0	55	0–5	1.0	97.7	92.7	99.4	0.00 1
	F3 09B9 1H1	375.0	60	0–7	1.6	96.5	89.9	98.9	0.001
Neg	F6 30C5 11A6	375.0	60	0–6	0.9	97.9	93.9	99.4	0.001
	F3 14A1 2H11	375.0	30	0–46	9.3	78.9	36.7	93.1	0.006
	Human serum	0	0	18–98	58.4
Pfs25	4B7	93.8	25	0 – 9	2.9	95.0	89.0	97.9	0.001
Neg Ctrl	F2 03G2 1A12	375.0	0	9 – 70	36.4
Pfs230	F3 09F4 5E1	375.0	80	0 – 1	0.2	99.5	98.8	99.8	0.001
	“	93.8	80	0 – 1	0.2	99.5	98.5	99.9	0.001
	F5 6D11 7E5	375.0	90	0–2	0.2	99.5	98.0	100.0	0.001
	“	93.8	70	0–4	0.6	98.4	95.2	100.0	0.001
	F5 05A6 2F5	75.0	0	6–72	31.1	14.6	−138.5	71.4	0.746
Pfs48/45	F2 14E5 1G9	375.0	5	0 – 46	16.4	54.9	0.1	79.5	0.050
	“	93.8	5	0 – 35	11.3	69.0	30.6	86.2	0.011
Pfs25	F5 04F5 2C7	375.0	70	0 – 3	0.6	98.5	96.4	99.4	0.001
	“	93.8	30	0 – 16	3.9	89.4	75.3	95.3	0.001
	F3 09B9 1H1	375.0	35	0 – 7	1.3	96.4	92.1	98.5	0.001
	“	93.8	5	0 – 28	9.4	74.2	34.7	90.7	0.003
Neg	F6 30C5 11A6	375.0	30	0 – 5	1.9	94.9	88.4	98.0	0.001
	“	93.8	5	0–34	13.3	63.6	16.4	84.0	0.017
	F3 14A1 2H11	375.0	0	2–47	22.3	38.6	−36.2	73.4	0.235
	“	93.8	5	0–39	18.1	50.3	−10.1	79.2	0.090