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. 2023 Jun 20;7:e45352. doi: 10.2196/45352

Table 1.

Related work in the literature.

Study Prediction methods Sample Sample size, n Outcomes AUROCa, best (95% CI) AUROC, best (outcome)
Gupta et al [11], 2022 Stepwise logistic regression, gradient boosting, and random forest Pediatric Heart Transplant Society database; aged <18 years; heart transplantation; discernible discharge date; transplanted between January 2005 to December 2018 4414 Prolonged length of stay (>30 days) after transplantation 0.750 (0.720-0.780) N/Ab
Killian et al [15], 2021 Logistic regression, multilayer perceptron, sequential minimal optimization algorithm polynomial kernel, random forest, and deep learning UNOSc data for a single transplant center; aged 0-18 years; heart transplant; transplanted between 1988 and May 31, 2017 193 Hospitalization owing to rejection over 1-, 3-, and 5-year posttransplant periods N/A 0.740 (5‐year hospitalization)
Miller et al [12], 2019 Artificial neural networks, classification and regression trees, and random forest UNOS data; aged <18 years; heart transplant; transplanted between January 2006 and December 2016 2802 Mortality over 1-, 3-, and 5-year posttransplant periods N/A 0.720 (1‐year mortality)
Miller et al [22], 2022 Random forest, XGBoostd, and L2 regularized logistic regression UNOS data; aged <18 years; heart transplant; transplanted between January 1994 and December 2016 8349 1-year and 90-day all-cause mortality 0.836 (0.823-0.849) N/A

aAUROC: area under the receiver operating characteristic curve.

bN/A: not applicable.

cUNOS: United Network for Organ Sharing.

dXGBoost: extreme gradient boosting.