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. 2023 Jul 3;13(11):3856–3871. doi: 10.7150/thno.82607

Figure 2.

Figure 2

H-Ki mice displayed attenuation of LI/R injury. A. Experimental protocol. LI/R was induced in mice. B. Mouse survival. Mice mortality was recorded after LI/R. **P < 0.01 by log-rank test, n = 68 in h-Ki group and n = 38 in WT group. C. Serum ALT and AST activities. Serum was collected from mice after sham or LI/R for measuring ALT and AST activities. Data are mean ± SD, ** P < 0.01 by two-way ANOVA followed by Tukey's test. n = 7/group. D. Histological examination. After sham or LI/R, liver tissues were collected, paraffin-embedded sectioned, and HE stained. Suzuki's scoring was performed and hepatic necrosis areas were measured to indicate histological injury. Scale bar = 200 μm. Data are mean ± SD, ** P < 0.01 by two-way ANOVA followed by Tukey's test. n = 8 for sham-WT group and n = 10 for all the other groups.