Table 3.

Summary of pharmacological treatments for primary delusional infestation.

Drug				Dose (mg/d)		Total number of patients, N		Duration, months		Outcomes
										Complete remission, n (%)		Partial remission, n (%)		No response, n (%)		Nonadherence, n (%)
First-generation antipsychotics (n=8)
	Total		—a		117		0.75-14		56 (47.9)		41 (35.0)		20 (17.1)		0 (0)
	Pimozide		2-8		80		3-14		35 (44)		27 (34)		18 (23)		0 (0)
	Haloperidol		1-10		10		0.75-14		6 (60)		4 (40)		0 (0)		0 (0)
	Fluphenazine depot		7.5-25		10		3-12		7 (70)		3 (30)		0 (0)		0 (0)
	Trifluoperazine		10, 15		6		0.75-2		3 (50)		2 (33)		1 (17)		0 (0)
	Flupentixol depot		2-20		5		3-12		4 (80)		0 (0)		1 (20)		0 (0)
	Chlorpromazine		150, 300		3		0.75-2		0 (0)		3 (100)		0 (0)		0 (0)
	Perphenazine		4,12		2		—		1 (50)		1 (50)		0 (0)		0 (0)
	Zuclopenthixol		6		1		—		0 (0)		1 (100)		0 (0)		0 (0)
Second-generation antipsychotics (n=9)
	Total		—		103		3-24		56 (54.4)		36 (35.0)		8 (7.8)		3 (2.9)
	Risperidone		0.5-4		44		3-24		19 (43)		18 (41)		5 (11)		2 (5)
	Olanzapine		2.5-10		22		3-24		12 (55)		9 (41)		1 (5)		0 (0)
	Aripiprazole		10-15		14		3-24		11 (79)		2 (14)		0 (0)		1 (7)
	Quetiapine		100, 400		7		6-24		4 (57)		3 (43)		0 (0)		0 (0)
	Amisulpride		—		7		6-24		3 (43)		3 (43)		1 (14)		0 (0)
	Paliperidone		—		5		6-24		4 (80)		1 (20)		0 (0)		0 (0)
	Iloperidone		—		2		6-24		2 (100)		0 (0)		0 (0)		0 (0)
	Melperone		50		1		—		1 (100)		0 (0)		0 (0)		0 (0)
	Sulpiride		—		1		—		0 (0)		0 (0)		1 (100)		0 (0)
Selective serotonin reuptake inhibitors (n=2)
		Total		—		21		6-24		12 (57)		9 (43)		0 (0)		0 (0)
		Fluoxetine		20		11		6-24		9 (82)		2 (18)		0 (0)		0 (0)
		Citalopram		—		10		—		3 (30)		7 (70)		0 (0)		0 (0)

^aEm dashes indicate “not reported”.