Table 1 .
Summary of characteristics and main findings in patients with PIMS-TS presenting with acute abdominal pain (n=19), patients numbered in order of date of admission.
| Pt. | Age (years) | M/F | Weight Centile (%) | Ethnicity | Abdo Pain | Vomiting | Bilious Vomiting | Diarrhoea | Fever | Abdominal Examination | Hb (g/l) | WCC (×109/l) | Neut (×109/l) | Lymph (×109/l) | CRP (mg/l) | Ferritin (μg/l) | Trop T (ng/l) | Fibrinogen (Clauss) (g/l) | D-Dimer (mg/l) | NT-proBNP (ng/l) | Image findingsUs=11, CT=8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 14 | M | 100 | Afro-Carribean | Y | N | N | Y | Y | General Tenderness | 77 | 14 | 12.3 | 1 | 463 | 2185 | 483 | 7 . 3 | 6 . 44 | 22,717 | CT: Fluid in RIF, marked caecal wall thickening, fat stranding, appendix not seen (Figure 2) |
| 2 | 8 | M | 80 | Afro-Carribean | Y | N | N | Y | Y | General Tenderness | 89 | 10.7 | 8.6 | 1.7 | 248 | 277 | 7 | 6 | 3 . 7 | 26 | US: Enlarged Liver, no other abnormalities |
| 3 | 4 | M | 75 | Middle-eastern | Y | Y | N | Y | Y | General Tenderness (+ distension) | 93 | 6.6 | 5.5 | 0.8 | 205 | 317 | 45 | 4 . 9 | 4 . 9 | 319 | US+CT: Moderate amount of ascites |
| 4 | 9 | M | 70 | Middle-eastern | Y | Y | Y | Y | Y | Localised RIF peritonitis | 92 | 9.8 | 8.9 | 0.5 | 178 | 1,332 | 112 | 6 . 1 | 10 . 4 | 9,353 | US: Localised RIF enlarged reactive lymph nodes with associated inflammatory changes, appendix not seen (Figure 1) |
| 5 | 12 | M | 80 | Afro-Carribean | Y | Y | N | Y | Y | Localised RIF peritonitis | 83 | 24 | 9.5 | 0.8 | 340 | 528 | 177 | 4 . 4 | 17 | 5,143 | CT (at local): Thick walled Gallbladder, free fluid in pelvis, thin walled appendix with appendicolith (Figure 3) |
| 6 | 13 | M | 80 | Middle-eastern | Y | Y | N | Y | Y | Right sided tenderness | 126 | 10.6 | 9.1 | 1 | 131 | 1,042 | 72 | 4 . 7 | 3 . 6 | 1,941 | CT: Free fluid in pelvis, no signs of appendicitis |
| 7 | 11 | F | 70 | Afro-Carribean | Y | Y | Y | Y | Y | Localised RIF peritonitis | 126 | 9.5 | 6.8 | 1.5 | 137 | 118 | 4 | 2.43 | 19 | No Imaging | |
| 8 | 6 | F | 30 | Chinese | Y | N | N | N | Y | General tenderness | 90 | 19 | 12.3 | 5.7 | 15 | 82 | 3 | 4 . 1 | 1 . 6 | 20 | US: Intermittent small bowel Intussusception |
| 9 | 16 | M | 60 | Caucasian | Y | Y | N | N | Y | Left sided tenderness | 109 | 8.2 | 3.7 | 3.2 | 108 | 418 | 8 | 3 . 3 | 1 . 14 | 1,573 | CT (at local): Enlarged mesenteric lymph nodes and fat stranding in the RIF |
| 10 | 14 | M | 100 | Afro-Carribean | Y | N | N | Y | Y | Right sided tenderness | 113 | 7.9 | 6.4 | 0.7 | 181 | 397 | 6 | 7 . 2 | 2 . 96 | 14 | CT (at local): Enlarged mesenteric lymph nodes |
| 11 | 16 | M | 90 | Middle-Eastern | Y | Y | N | Y | Y | Localised RIF peritonitis | 136 | 9 | 7.1 | 1.2 | 287 | 3 | 7 . 1 | 2 . 2 | 40 | CT: Terminal ileitis, mesenteric lymph nodes, no free fluid, appendix not visualised | |
| 12 | 7 | M | 85 | Middle-Eastern | Y | Y | N | Y | Y | General Tenderness | 92 | 13 | 8.4 | 1.3 | 167 | 400 | 89 | 7 | 3.76 | 12,567 | US: Gallbladder distended, trace free fluid RIF, normal appendix |
| 13 | 9 | M | 95 | Afro-Carribean | Y | Y | N | Y | Y | Right sided tenderness | 123 | 9.9 | 7.3 | 1.4 | 152 | 565 | 16 | 1 . 3 | 5 . 3 | 584 | US: Normal |
| 14 | 12 | M | 100 | Afro-Carribean | Y | Y | N | N | Y | General Tenderness (+ distension) | 104 | 9.1 | 6.6 | 1.8 | 176 | 89 | 9 | 2 . 6 | 1 . 9 | 229 | US: Normal |
| 15 | 9 | M | 20 | Caucasian | Y | N | N | Y | Y | General Tenderness (+ distension) | 116 | 14 | 11.2 | 2.2 | 45 | 65 | 6 | 4 . 9 | 0 . 41 | 106 | US: Normal |
| 16 | 4 | M | 50 | Caucasian | Y | Y | N | Y | Y | General Tenderness | 108 | 10.5 | 8.9 | 1.1 | 216 | 172 | 3 | 6 . 8 | 10 . 6 | 482 | US: Normal |
| 17 | 10 | M | 100 | Afro-Carribean | Y | N | N | Y | Y | Not Tender | 142 | 6.1 | 5.0 | 0.9 | 220 | 216 | 5 | 6 . 1 | 22 . 0 | 29 | US: Normal |
| 18 | 5 | F | 65 | Caucasian | Y | Y | N | N | Y | Localised RIF peritonitis | 125 | 22.0 | 19.2 | 2.3 | 161 | 151 | 3 | 5 . 8 | 0 . 61 | 535 | No Imaging |
| 19 | 12 | M | 50 | Afro-Carribean | Y | N | N | N | Y | General Tenderness | 113 | 5.5 | 4.2 | 0.6 | 119 | 118 | 4 | 5 . 6 | 2 . 37 | 158 | US+CT: Bowel wall thickening in keeping with colitis |
M = Male, F = Female, Y = Yes, N = No Hb = Haemoglobin, WCC = White Cell Count, Neut = Neutrophils, Lymph = Lymphocytes, CRP = C-Reactive Protein, Trop T = Troponin T, NT-proBNP = N-Terminal Prohormone of Brain Natriuretic Peptide, PIMS-TS = Paediatric Inflammatory Multisystem Syndrome – Temporally Associated with SARS-CoV-2, RIF = Right Iliac Fossa, US = Ultrasound Scan.