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. 2022 May;104(5):380–384. doi: 10.1308/rcsann.2021.0196

Table 1 .

Characteristics of clinical variables in patients with benign and malignant nodules

Clinical Variants Benign nodules
(n=29)
Malignant nodules
(n=11)
p-value
Age, years (SD) 52.1 (13) 56.6 (18) 0.232
Female:male, n (%) 25:4 (63:10) 9:2 (23:5) 0.541
Family history of thyroid carcinoma, n (%) 1 (3) 1 (9)
Exposure to cervical radiation, n (%) 0 (0) 0 (0)
Solid nodules, n (%) 23 (79) 9 (81) 0.622
Irregular margins, n (%) 22 (76) 8 (73) 0.631
Hypoechogenicity, n (%) 24 (82) 9 (81) 0.762
Microcalcifications, n (%) 8 (28) 4 (36) 0.431
Solitary nodule, n (%) 15 (52) 2 (18) 0.079
Serum TSH (median) 1.56 (1.09–2.05) 2.73 (1.40–3.66) 0.025
FLUS/AUS/ n (%) 20/9 (83/56) 7/4 (44/16) 0.453

Values ​​are shown as Mean (SD) or median (25th to 75th percentile). Microcalcifications and number of nodules were evaluated by ultrasound.