Fig. 1.
(a) Denaturing PAGE image showing products of the ldh1 iSDA assay in a few selected porous materials. Only Std 17 GF showed the targeted amplification product bands at ~100 and 120 nucleotides (green arrow) comparable to the assay as performed in-tube (conventional polypropylene tube). The inevitable primer dimer side products are indicated with a red arrow. Quartz (QMA), nitrocellulose (NC-FF80), and Fusion 5 totally inhibited amplification, including the primer-dimer side reactions. (b) Gel image showing the effect of leachate from porous materials on iSDA as performed in a tube. Leachate from NC-FF80, Fusion 5, and cellulose significantly inhibited iSDA as seen by very faint product-specific products, whereas the leachate from QMA did not affect the iSDA assay.