Table 5.
Summary of SNP-SNP Interactions on the Risk of Stroke Analyzed by MDR Method
| Model | Training Bal. Acc | Testing Bal. Acc | CVC | OR (95% CI) | p |
|---|---|---|---|---|---|
| rs9808753* | 0.529 | 0.529 | 10/10 | 1.31 (1.02–1.68) | 0.036 |
| rs369149111, rs9808753 | 0.534 | 0.504 | 10/10 | 1.39 (1.07–1.82) | 0.015 |
| rs369149111, rs1803628, rs9808753 | 0.540 | 0.490 | 10/10 | 1.38 (1.09–1.76) | 0.008 |
Notes: p values were calculated using χ2 test. p < 0.05 in bold type indicates statistical significance. *The best model in MDR analysis.
Abbreviations: MDR, multifactor dimensionality reduction; Bal. Acc, balanced accuracy; CVC, cross-validation consistency; OR, odds ratio; 95% CI, 95% confidence interval.