| Study | Reason for exclusion |
|---|---|
| Aboulghar 1995 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Aboulghar 1996 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Agarwal 2004 | Unexplained subfertility couples |
| Buvat 1990 | Number of couples receiving IUI and TI was not stated |
| Crosignani 1994 | Authors could not provide pre‐cross‐over data |
| Cruz 1986 | Different comparison: IUI vs. ICI |
| Elizur 2004 | Not an RCT, but a retrospective study |
| Elzeiny 2014 | Unexplained subfertility couples |
| Evans 1991 | Biochemical pregnancies only, no response from the author |
| Fan 2012 | Oocytes were randomised between IVF and ICSI, no outcome data available per couple |
| Fishel 2000 | Oocytes were randomised between IVF and ICSI, no outcome data available per couple |
| Friedman 1989 | Preliminary report, different comparison: IUI vs. ICI |
| Galle 1990 | Not an RCT, but an observational study |
| Goverde 2001 | Not an RCT, correspondence |
| Hewitt 1985 | Not an RCT, an observational study |
| Ho 1989 | Authors could not provide pre‐cross‐over data |
| Ho 1992 | Authors could not provide pre‐cross‐over data |
| Karlström 2000 | Compares IUI both with different forms of OH |
| Kastrop 1999 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Kihaile 2003 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Kirby 1991 | Authors could not provide pre‐cross‐over data |
| Li 2004 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Martinez 1991 | Authors could not provide pre‐cross‐over data |
| Melis 1987 | Different comparison: ICI in natural cycle vs. ICI with OH |
| Moolenaar 2015 | Not an RCT, but a retrospective study |
| Nulsen 1993 | Not an RCT: quasi randomised, biochemical pregnancies only |
| Pisarska 1999 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Plachot 2002 | Not an RCT: oocytes were quasi randomised between IVF and ICSI |
| Prentice 1995 | Not an RCT: quasi randomised, based on hospital case record number |
| Soliman 1993 | Incomplete data on treatment of control group |
| te Velde 1989 | Authors could not provide pre‐cross‐over data |
| Tournaye 2002 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| van der Westerlaken 2006 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Verheyen 1999 | Oocytes were randomly divided between IVF and ICSI, no outcome data available per couple |
| Xie 2015 | Not an RCT |
| Zayed 1997 | Not an RCT: quasi randomised, patient preference |
ICI: intra‐cervical insemination; ICSI: intracytoplasmic sperm injection; IUI: intra‐uterine insemination; IVF: in vitro fertilisation; OH: ovarian hyperstimulation; RCT: randomised controlled trial; TI: timed intercourse.